SCHEMBL4082456

SCHEMBL4082456

CO[Si](CI)(CCc1ccccc1)CCc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46
ALOX12 P18054 1/20 0.46
CASP1 P29466 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 2/20 0.40
TAAR1 Q96RJ0 3/20 0.36
ATM Q13315 1/20 0.36
CYP2A6 P11509 1/20 0.35
HTR2A P28223 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
LOXL2 Q9Y4K0 1/20 0.35
KCNH2 Q12809 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
IDO1 P14902 1/20 0.34
AOC3 Q16853 1/20 0.34
LTA4H P09960 1/20 0.34
CA12 O43570 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17750070 0.88 TDP1 (0.46) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL4076369 0.81 ALDH1A1 (0.43) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL4077203 0.81 TDP1 (0.40) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL4075450 0.81 ALDH1A1 (0.46) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL4077066 0.81 TDP1 (0.45) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL4073992 0.80 HPGD (0.42) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL4079216 0.79 HPGD (0.41) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL9716603 0.75 TDP1 (0.46) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL106416 0.75 TDP1 (0.46) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL1584725 0.74 TDP1 (0.44) ALDH1A1HPGDALOX15ALOX12CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1705207-B1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR CORP (JP) 2012-10-24 EP disclosed
US-7528207-B2 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2009-05-05 US disclosed
US-20070021580-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-25 US disclosed
US-20070015892-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-18 US disclosed
EP-1705206-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed
EP-1705207-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed