SCHEMBL4079216

SCHEMBL4079216

CCCO[Si](CI)(CCc1ccccc1)CCc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.41
ALDH1A1 P00352 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
CASP1 P29466 1/20 0.41
HSD17B10 Q99714 1/20 0.41
RAB9A P51151 4/20 0.37
NPC1 O15118 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
MAPT P10636 1/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
TDP1 Q9NUW8 1/20 0.35
IDO1 P14902 1/20 0.34
SIGMAR1 Q99720 3/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4076369 0.86 ALDH1A1 (0.43) HPGDALDH1A1ALOX15ALOX12CASP1
SCHEMBL4077436 0.83 TDP1 (0.39) RAB9ANPC1SMN1; SMN2MAPTNFKB1
SCHEMBL4082994 0.83 HPGD (0.41) HPGDALDH1A1ALOX15ALOX12CASP1
SCHEMBL4084761 0.83 RAB9A (0.37) HPGDALDH1A1ALOX12RAB9ANPC1
SCHEMBL4082456 0.79 ALDH1A1 (0.46) HPGDALDH1A1ALOX15ALOX12CASP1
SCHEMBL20658023 0.79 RAB9A (0.40) HPGDALDH1A1ALOX15ALOX12CASP1
SCHEMBL106648 0.79 RAB9A (0.40) HPGDALDH1A1ALOX15ALOX12CASP1
SCHEMBL4073992 0.75 HPGD (0.42) HPGDALDH1A1ALOX15ALOX12CASP1
SCHEMBL28065352 0.75 RAB9A (0.38) RAB9ANPC1SMN1; SMN2MAPTNFKB1
SCHEMBL6332013 0.75 RAB9A (0.38) RAB9ANPC1SMN1; SMN2MAPTNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1705207-B1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR CORP (JP) 2012-10-24 EP disclosed
US-7528207-B2 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2009-05-05 US disclosed
US-20070021580-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-25 US disclosed
US-20070015892-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-18 US disclosed
EP-1705206-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed
EP-1705207-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed