Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HRH2 | P25021 | 3/20 | 0.42 |
| ▸ | HRH1 | P35367 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17017 | 0.98 | POLB (0.63) | POLBSMN1; SMN2LMNAALDH1A1HRH2 | |
| SCHEMBL18760256 | 0.98 | POLB (0.63) | POLBSMN1; SMN2LMNAALDH1A1HRH2 | |
| SCHEMBL5820669 | 0.98 | POLB (0.63) | POLBSMN1; SMN2LMNAALDH1A1HRH2 | |
| Hydrochloric Acid SCHEMBL1111003 | 0.97 | POLB (0.61) | POLBSMN1; SMN2LMNAALDH1A1HRH2 | |
| Potassium SCHEMBL30906131 | 0.97 | POLB (0.61) | POLBSMN1; SMN2LMNAALDH1A1HRH2 | |
| SCHEMBL5667296 | 0.93 | LMNA (0.57) | POLBSMN1; SMN2LMNAHRH2HRH1 | |
| SCHEMBL112600 | 0.92 | SMN1; SMN2 (0.56) | POLBSMN1; SMN2LMNAALDH1A1HRH2 | |
| SCHEMBL25424462 | 0.92 | LMNA (0.55) | POLBSMN1; SMN2LMNAGNAI3GNAO1 | |
| SCHEMBL27694189 | 0.92 | LMNA (0.55) | POLBSMN1; SMN2LMNAGNAI3GNAO1 | |
| SCHEMBL9123475 | 0.92 | LMNA (0.55) | POLBSMN1; SMN2LMNAGNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041571-A1 | LUMINEESCENCE ASSAY USING MACROCYCLIC LANTHANIDE ( III ) COMPLEXES | UNIVERSITY OF DURHAM (GB) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008007089-A1 | LUMINEESCENCE ASSAY USING MACROCYCLIC LANTHANIDE ( III ) COMPLEXES | UNIVERSITY OF DURHAM (GB) | 2008-01-17 | — | — | WO | disclosed |