Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | FADS1 | O60427 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL206834 | 0.97 | DHODH (0.48) | DHODHSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL207293 | 0.94 | DHODH (0.48) | DHODHSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL205940 | 0.92 | DHODH (0.55) | DHODHSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL205814 | 0.87 | LMNA (0.44) | DHODHSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL5160034 | 0.87 | DHODH (0.40) | DHODHSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL206084 | 0.84 | EPHX2 (0.47) | EPHX2THRBHPGDSIGMAR1 | |
| SCHEMBL5158451 | 0.83 | DHODH (0.35) | DHODHMEN1KMT2ATHRBNPSR1 | |
| SCHEMBL206620 | 0.82 | EPHX2 (0.46) | ALDH1A1EPHX2THRBHPGDSIGMAR1 | |
| SCHEMBL207557 | 0.82 | LMNA (0.52) | DHODHSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL206966 | 0.81 | EPHX2 (0.62) | MEN1KMT2AEPHX2THRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | claimed |