SCHEMBL4083016

SCHEMBL4083016

C=CC(=O)N(C)c1ccc2ccccc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.49
MAPT P10636 2/20 0.49
MAPK1 P28482 2/20 0.49
HSD17B10 Q99714 2/20 0.49
MEN1 O00255 1/20 0.49
ALDH1A1 P00352 1/20 0.49
EGFR P00533 1/20 0.49
TP53 P04637 1/20 0.49
CYP3A4 P08684 1/20 0.49
PKM P14618 1/20 0.49
HPGD P15428 1/20 0.49
ALOX15 P16050 1/20 0.49
ALOX12 P18054 1/20 0.49
JAK1 P23458 1/20 0.49
KMT2A Q03164 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
PSMB5 P28074 1/20 0.43
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21268574 0.83 ALDH1A1 (0.51) KDM4EMAPTMAPK1HSD17B10MEN1
SCHEMBL30804118 0.83 ALDH1A1 (0.51) KDM4EMAPTMAPK1HSD17B10MEN1
SCHEMBL1695083 0.79 ACHE (0.46) KDM4EMAPTMAPK1HSD17B10MEN1
SCHEMBL1137614 0.79 PDK2 (0.47) KDM4EMAPTMAPK1HSD17B10MEN1
SCHEMBL4903337 0.79 ALDH1A1 (0.48) KDM4EMAPTMAPK1HSD17B10MEN1
SCHEMBL319608 0.78 KMT2A (0.46) KDM4EMAPTMEN1ALDH1A1PKM
SCHEMBL14385153 0.77 PLAU (0.45) KDM4EMAPTMAPK1HSD17B10MEN1
SCHEMBL26219236 0.77 THRA (0.47) KDM4EALDH1A1
SCHEMBL10438892 0.77 KMT2A (0.44) KDM4EMAPTMEN1ALDH1A1PKM
SCHEMBL1176870 0.77 ESR1 (0.49) KDM4EMAPTMAPK1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7500895-B2 Patterned substrate, electro-optical device, and method for manufacturing an electro-optical device SEIKO EPSON CORPORATION (JP) 2009-03-10 US disclosed
CN-1790772-A Patterned substrate, electro-optical device, and method for manufacturing an electro-optical device SEIKO EPSON CORP (JP) 2006-06-21 CN disclosed
US-20060127563-A1 Patterned substrate, electro-optical device, and method for manufacturing an electro-optical device SEIKO EPSON CORPORATION (JP) 2006-06-15 US disclosed
US-20050287392-A1 Organic electroluminescent device, method for producing the same, and electronic apparatus SEIKO EPSON CORPORATION (JP) 2005-12-29 US disclosed