SCHEMBL4083044

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3250083	1.00	CHEK1 (0.37)	CHEK1MAPK14LMNAGAAYEATS4
	SCHEMBL3240789	1.00	CHEK1 (0.37)	CHEK1MAPK14LMNAGAAYEATS4
	SCHEMBL3253614	0.94	CDK4 (0.39)	MAPK14SPRHDAC4HDAC1HDAC6
	SCHEMBL4083448	0.94	CDK4 (0.39)	MAPK14SPRHDAC4HDAC1HDAC6
	SCHEMBL3247320	0.94	CDK4 (0.39)	MAPK14SPRHDAC4HDAC1HDAC6
	SCHEMBL19775144	0.90	MAPK14 (0.37)	MAPK14LMNAGAAYEATS4MEN1
	SCHEMBL4094743	0.90	HDAC4 (0.39)	MAPK14LMNAGAAYEATS4MEN1
	SCHEMBL11355346	0.90	POLB (0.42)	MAPK14LMNAGAAMEN1KMT2A
	SCHEMBL8096953	0.90	POLB (0.42)	MAPK14LMNAGAAMEN1KMT2A
	SCHEMBL3247228	0.90	HDAC4 (0.39)	MAPK14LMNAGAAYEATS4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.