SCHEMBL4094743

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3247824	1.00	HDAC4 (0.39)	HDAC4MAPTKMT2ADYRK3ROCK2
	SCHEMBL3247228	1.00	HDAC4 (0.39)	HDAC4MAPTKMT2ADYRK3ROCK2
	SCHEMBL8096953	0.90	POLB (0.42)	MAPTKMT2AMAPK14LMNAGAA
	SCHEMBL19775144	0.90	MAPK14 (0.37)	HDAC4KMT2AMAPK14LMNAGAA
	SCHEMBL11355346	0.90	POLB (0.42)	MAPTKMT2AMAPK14LMNAGAA
	SCHEMBL3249522	0.90	HDAC4 (0.37)	HDAC4MAPK14LMNARORCSPR
	SCHEMBL3240789	0.90	CHEK1 (0.37)	HDAC4KMT2AMAPK14LMNAGAA
	SCHEMBL3250580	0.90	SPR (0.41)	KMT2AMEN1SPRRAB9A
	SCHEMBL4083044	0.90	CHEK1 (0.37)	HDAC4KMT2AMAPK14LMNAGAA
	SCHEMBL3250083	0.90	CHEK1 (0.37)	HDAC4KMT2AMAPK14LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.