Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28669991 | 0.82 | ALDH1A1 (0.79) | ALDH1A1TSHRKDM4EMEN1MAPT | |
| SCHEMBL3005458 | 0.81 | GAA (0.52) | GAAALDH1A1TSHRKDM4EMEN1 | |
| SCHEMBL3129599 | 0.80 | ALDH1A1 (0.72) | GAAALDH1A1TSHRKDM4EMEN1 | |
| SCHEMBL28162015 | 0.80 | GAA (1.00) | GAAALDH1A1TSHRKDM4EMEN1 | |
| SCHEMBL6706771 | 0.77 | GAA (0.73) | GAAALDH1A1TSHRKDM4EMEN1 | |
| SCHEMBL3002479 | 0.73 | GAA (0.71) | GAAALDH1A1TSHRKDM4EMEN1 | |
| SCHEMBL6705726 | 0.71 | ALDH1A1 (0.81) | GAAALDH1A1TSHRKDM4EMEN1 | |
| SCHEMBL3002928 | 0.70 | ALDH1A1 (0.35) | GAAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2995442 | 0.70 | KDM4E (0.61) | GAAALDH1A1TSHRKDM4EMEN1 | |
| SCHEMBL6706698 | 0.70 | ALDH1A1 (0.79) | ALDH1A1TSHRKDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009006580-A1 | OPTIONALLY CONDENSED DIHYDROPYRIDINE, DIHYDROPYRIMIDINE AND DIHYDROPYRANE DERIVATIVES ACTING AS LATE SODIUM CHANNEL BLOCKERS | CV THERAPEUTICS, INC. (US) | 2009-01-08 | — | — | WO | disclosed |