Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | SLC29A1 | Q99808 | 7/20 | 0.72 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.72 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.72 |
| ▸ | PGK1 | P00558 | 1/20 | 0.69 |
| ▸ | PGK2 | P07205 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | NT5E | P21589 | 1/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.66 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.65 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.65 |
| ▸ | DPP4 | P27487 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.63 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.63 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.63 |
| ▸ | GAPDH | P04406 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | STAT6 | P42226 | 1/20 | 0.63 |
| ▸ | PI4KA | P42356 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thioguanosine SCHEMBL608145 | 1.00 | CYP2C19 (0.73) | CYP2C19SLC29A1ADORA3ADORA1PGK1 | |
| Thioguanosine SCHEMBL23927999 | 1.00 | CYP2C19 (0.73) | CYP2C19SLC29A1ADORA3ADORA1PGK1 | |
| Thioguanosine SCHEMBL6748957 | 1.00 | CYP2C19 (0.73) | CYP2C19SLC29A1ADORA3ADORA1PGK1 | |
| Thioguanosine SCHEMBL8185769 | 1.00 | CYP2C19 (0.73) | CYP2C19SLC29A1ADORA3ADORA1PGK1 | |
| Thioguanosine SCHEMBL8612570 | 0.99 | CYP2C19 (0.72) | CYP2C19SLC29A1ADORA3ADORA1PGK1 | |
| Thioguanosine SCHEMBL8612560 | 0.99 | CYP2C19 (0.72) | CYP2C19SLC29A1ADORA3ADORA1PGK1 | |
| Thioguanosine SCHEMBL3861782 | 0.94 | CYP2C19 (0.67) | CYP2C19SLC29A1ADORA3ADORA1PGK1 | |
| Thioguanosine SCHEMBL3294897 | 0.94 | CYP2C19 (0.67) | CYP2C19SLC29A1ADORA3ADORA1PGK1 | |
| Thioguanosine SCHEMBL11084568 | 0.93 | CYP2C19 (0.69) | CYP2C19SLC29A1ADORA3ADORA1PGK1 | |
| Thioguanosine SCHEMBL3928265 | 0.91 | CYP2C19 (0.62) | CYP2C19SLC29A1ADORA3ADORA1PGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355472-B2 | ACID PHOSPHATASE | AJINOMOTO CO., INC. (JP) | 2002-03-12 | — | — | US | claimed |
| US-20020004590-A1 | Method for producing nucleoside-5'-phosphate ester | MIHARA YASUHIRO (JP) | 2002-01-10 | — | — | US | claimed |
| US-6207435-B1 | MUTANT ACID PHOSPHATASE HAVING DECREASED MICHAELIS CONSTANT FOR A NUCLEOSIDE AND/OR INCREASED TEMPERATURE STABILITY; FOR EFFICIENT PHOSPHORYLATION OF NUCLEOSIDES TO PRODUCE NUCLEOTIDES | AJINOMOTO CO., INC. (JP) | 2001-03-27 | — | — | US | claimed |
| US-6015697-A | ECONOMICAL AND EFFICIENT PROCESS BY REACTING A NUCLEOSIDE WITH A PHOSPHATE DONOR GROUP IN PRESENCE OF MUTANT ACID PHOSPHATASE WITH DECREASED MICHAELIS CONSTANT FOR NUCLEOSIDE OR INCREASED TEMPERATURE STABILITY | AJINOMOTO CO., INC. (JP) | 2000-01-18 | — | — | US | claimed |
| WO-2019195494-A1 | COMPOSITIONS AND METHODS FOR SYNTHESIS OF PHOSPHORYLATED MOLECULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-10-10 | — | — | WO | disclosed |
| US-7575901-B2 | Propagating escherichia mutant which produces 5'-inosinic acid or 5'-guanylic acid; identifying nucleotidase gene associated with generating nucleoside 5'-phosphate esters | AJINOMOTO CO., INC. (JP) | 2009-08-18 | — | — | US | disclosed |
| EP-1392639-B1 | PYRUVATE DERIVATIVES | GALILEO LAB INC (US) | 2008-09-17 | — | — | EP | disclosed |
| US-7385051-B2 | Fluorescent N2,N3-etheno-purine (2′-deoxy) riboside derivatives and uses thereof | BAR-LLAN UNIVERSITY (IL) | 2008-06-10 | — | — | US | disclosed |
| US-20080026428-A1 | METHOD FOR PRODUCING NUCLEOTIDE BY FERMENTATION | AJINOMOTO CO., INC. (JP) | 2008-01-31 | — | — | US | disclosed |
| EP-0832970-B1 | PROCESS FOR PRODUCING NUCLEOSIDE-5'-PHOSPHATE ESTER | AJINOMOTO KK (JP) | 2007-01-17 | — | — | EP | disclosed |
| EP-1170370-B1 | Method for producing nucleotide by fermentation | AJINOMOTO KK (JP) | 2006-09-27 | — | — | EP | disclosed |
| US-20060166248-A1 | Fluorescent N2, N3-etheno-purine (2'deoxy) riboside derivatives and uses thereof | BAR-ILAN UNIVERSITY (IL) | 2006-07-27 | — | — | US | disclosed |
| US-20020098494-A1 | Method for producing nucleotide by fermentation | AJINOMOTO CO., INC. (JP) | 2002-07-25 | — | — | US | disclosed |
| US-6355472-B2 | ACID PHOSPHATASE | AJINOMOTO CO., INC. (JP) | 2002-03-12 | — | — | US | disclosed |
| EP-1170370-A2 | Method for producing nucleotide by fermentation | Ajinomoto Co., Inc. (JP) | 2002-01-09 | — | — | EP | disclosed |
| US-6207435-B1 | MUTANT ACID PHOSPHATASE HAVING DECREASED MICHAELIS CONSTANT FOR A NUCLEOSIDE AND/OR INCREASED TEMPERATURE STABILITY; FOR EFFICIENT PHOSPHORYLATION OF NUCLEOSIDES TO PRODUCE NUCLEOTIDES | AJINOMOTO CO., INC. (JP) | 2001-03-27 | — | — | US | disclosed |
| US-6015697-A | ECONOMICAL AND EFFICIENT PROCESS BY REACTING A NUCLEOSIDE WITH A PHOSPHATE DONOR GROUP IN PRESENCE OF MUTANT ACID PHOSPHATASE WITH DECREASED MICHAELIS CONSTANT FOR NUCLEOSIDE OR INCREASED TEMPERATURE STABILITY | AJINOMOTO CO., INC. (JP) | 2000-01-18 | — | — | US | disclosed |
| US-6010851-A | ALLOWING AN ACID PHOSPHATASE HAVING A LOWERED PHOSPHOMONOESTERASE ACTIVITY TO ACT UNDER A CONDITION OF PH 3.0 TO 5.5 ON A NUCLEOSIDE AND A PHOSPHATE GROUP DONOR | AJINOMOTO CO., INC. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0857788-A2 | Method for producing nucleoside-5'-phosphate ester | Ajinomoto Co., Inc. (JP) | 1998-08-12 | — | — | EP | disclosed |
| EP-0832970-A1 | PROCESS FOR PRODUCING NUCLEOSIDE-5'-PHOSPHATE | Ajinomoto Co., Inc. (JP) | 1998-04-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166248-A1 | Fluorescent N2, N3-etheno-purine (2'deoxy) riboside derivatives and uses thereof | NUDT1, NT5C2, DUT | CYP2C19 4370/4885SLC29A1 118/4885ADORA3 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.