SCHEMBL408356

SCHEMBL408356

CC#COc1cccc2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTR1B P28222 9/20 0.43
ALDH1A1 P00352 3/20 0.43
HSD17B10 Q99714 3/20 0.43
PGR P06401 1/20 0.43
GAA P10253 1/20 0.43
PTGS1 P23219 1/20 0.43
MAPK1 P28482 1/20 0.43
HTR1D P28221 1/20 0.43
SLC6A4 P31645 2/20 0.42
KDM4E B2RXH2 2/20 0.42
HRH1 P35367 1/20 0.42
KCNA3 P22001 1/20 0.41
HPGD P15428 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1127922 0.75 HTR1B (0.46) HTR1BALDH1A1HSD17B10PGRGAA
SCHEMBL822708 0.75 HTR1B (0.46) HTR1BALDH1A1HSD17B10PGRGAA
SCHEMBL27467534 0.75 HTR1B (0.46) HTR1BALDH1A1HSD17B10PGRGAA
SCHEMBL30725930 0.75 HTR1B (0.46) HTR1BALDH1A1HSD17B10PGRGAA
SCHEMBL2945 0.75 ALDH1A1 (0.47) HTR1BALDH1A1HSD17B10PGRGAA
SCHEMBL1306414 0.74 HTR1B (0.42) HTR1BALDH1A1HSD17B10PGRGAA
Hydrogen Sulfide SCHEMBL28001728 0.73 HTR1B (0.44) HTR1BALDH1A1HSD17B10PGRGAA
SCHEMBL9281834 0.72 TSHR (0.42) ALDH1A1KDM4ETDP1KMT2A
Acetonitrile SCHEMBL28116095 0.72 MAPT (0.52) HTR1BALDH1A1HSD17B10PGRGAA
SCHEMBL29367279 0.72 MAPT (0.61) HTR1BALDH1A1HSD17B10PGRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748834-A1 NOVEL HYDRAZONE DERIVATIVE AND AGENT FOR AGRICULTURAL AND HORTICULTURAL USE CONTAINING SAME AS ACTIVE INGREDIENT Agro-Kanesho Co., Ltd. (JP) 2026-05-27 EP disclosed
US-12279617-B2 Agricultural and horticultural chemical agent containing new imidazopyridine-2-carboxamide derivative as active ingredient AGRO-KANESHO CO., LTD. (JP) 2025-04-22 US disclosed
WO-2025018390-A1 NOVEL HYDRAZONE DERIVATIVE AND AGENT FOR AGRICULTURAL AND HORTICULTURAL USE CONTAINING SAME AS ACTIVE INGREDIENT アグロカネショウ株式会社 2025-01-23 WO disclosed
EP-3985004-B1 AGRICULTURAL AND HORTICULTURAL CHEMICAL AGENT CONTAING NEW IMIDAZOPYRIDINE-2-CARBOXAMIDE DERIVATIVE AS ACTIVE INGREDIENT AGRO KANESHO CO LTD (JP) 2024-09-04 EP disclosed
CN-114008045-B Agricultural and horticultural agent containing novel imidazopyridine-2-carboxamide derivative as active ingredient 阿格罗-金正株式会社 2024-07-16 CN disclosed
CN-116264894-B Preparation and application of 1-pyridylpyrazole amide compound 湖南化工研究院有限公司 2024-07-09 CN disclosed
WO-2024117205-A1 BICYCLIC PYRIDINE DERIVATIVE AND SALT THEREOF, AND HARMFUL ORGANISM CONTROL AGENT CHARACTERIZED BY CONTAINING SAID DERIVATIVE OR SALT THEREOF AS ACTIVE INGREDIENT 北興化学工業株式会社 2024-06-06 WO disclosed
CN-116264894-A Preparation and application of 1-pyridylpyrazole amide compound 湖南化工研究院有限公司 2023-06-20 CN disclosed
US-20220330550-A1 AGRICULTURAL AND HORTICULTURAL CHEMICAL AGENT CONTAINING NEW IMIDAZOPYRIDINE-2-CARBOXAMIDE DERIVATIVE AS ACTIVE INGREDIENT AGRO-KANESHO CO., LTD. (JP) 2022-10-20 US disclosed
EP-3985004-A1 AGRICULTURAL AND HORTICULTURAL CHEMICAL AGENT HAVING NOVEL IMIDAZOPYRIDINE-2-CARBOXAMIDE DERIVATIVE AS ACTIVE INGREDIENT Agro-Kanesho Co., Ltd. (JP) 2022-04-20 EP disclosed
EP-2394986-B1 3-AMINOXALYLAMINOBENZAMIDE DERIVATIVES, AND INSECTICIDAL AND MITICIDAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENT AGRO KANESHO CO LTD (JP) 2013-12-04 EP disclosed
US-8541473-B2 3-aminoxalyl-aminobenzamide derivatives and insecticidal and miticidal agents containing same as active ingredient AGRO-KANESHO CO., LTD. (JP) 2013-09-24 US disclosed
CN-102378754-A 3-aminoxalylaminobenzamide derivatives, and insecticidal and miticidal agents containing same as active ingredient AGRO KANESHO CO LTD 2012-03-14 CN disclosed
US-20120022263-A1 3-AMINOXALYL-AMINOBENZAMIDE DERIVATIVES AND INSECTICIDAL AND MITICIDAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENT AGRO-KANESHO CO., LTD. (JP) 2012-01-26 US disclosed
EP-2394986-A1 3-AMINOXALYLAMINOBENZAMIDE DERIVATIVES, AND INSECTICIDAL AND MITICIDAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENT Agro-Kanesho Co., Ltd. (JP) 2011-12-14 EP disclosed
EP-0862545-B1 PESTICIDE COMPOUNDS, COMPOSITIONS AND PROCESS FOR THE PREPARATION THEREOF AGRO CHEMIE NOEVENYVEDOESZER G (HU) 2003-06-04 EP disclosed
US-6277867-B1 SYNERGISTIC MIXTURES CHINOIN GYOGYSZER ES VEGYESZETI (HU) 2001-08-21 US disclosed
EP-0862545-A2 PESTICIDE COMPOUNDS, COMPOSITIONS AND PROCESS FOR THE PREPARATION THEREOF CHINOIN Gyògyszer és Vegyészeti Termékek Gyára RT. (HU) 1998-09-09 EP disclosed
WO-1997019040-A9 PESTICIDE COMPOUNDS, COMPOSITIONS AND PROCESS FOR THE PREPARATION THEREOF 1997-08-07 WO disclosed
WO-1997019040-A2 PESTICIDE COMPOUNDS, COMPOSITIONS AND PROCESS FOR THE PREPARATION THEREOF Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) 1997-05-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12279617-B2 Agricultural and horticultural chemical agent containing new imidazopyridine-2-carboxamide derivative as active ingredient CBR3, HRH4, H1-0 HTR1B 1823/4885ALDH1A1 770/4885HSD17B10 2341/4885
US-20120022263-A1 3-AMINOXALYL-AMINOBENZAMIDE DERIVATIVES AND INSECTICIDAL AND MITICIDAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENT HDHD5, CBR3, BAK1 HTR1B 266/4885ALDH1A1 889/4885HSD17B10 1318/4885
US-20220330550-A1 AGRICULTURAL AND HORTICULTURAL CHEMICAL AGENT CONTAINING NEW IMIDAZOPYRIDINE-2-CARBOXAMIDE DERIVATIVE AS ACTIVE INGREDIENT CBR3, HRH4, H1-0 HTR1B 1801/4885ALDH1A1 971/4885HSD17B10 2645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.