Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4084006 | 1.00 | FFAR4 (0.43) | FFAR4BACE1SLC6A11PTGER1PTGER3 | |
| SCHEMBL18172807 | 0.80 | NFE2L2 (0.46) | RECQLKMT2A | |
| SCHEMBL18172808 | 0.80 | NFE2L2 (0.46) | RECQLKMT2A | |
| SCHEMBL18172738 | 0.77 | KDM1A (0.56) | RECQL | |
| SCHEMBL18173266 | 0.77 | KDM1A (0.56) | RECQL | |
| SCHEMBL18172735 | 0.77 | KDM1A (0.56) | RECQL | |
| SCHEMBL6835912 | 0.74 | BACE1 (0.55) | BACE1SLC6A11PTGER1PTGER3PTGER2 | |
| SCHEMBL6835913 | 0.74 | BACE1 (0.55) | BACE1SLC6A11PTGER1PTGER3PTGER2 | |
| SCHEMBL284706 | 0.70 | GRIN2D (0.48) | BACE1PTGER1PTGER3PTGER2GRIN2D | |
| SCHEMBL27643067 | 0.70 | GRIN2D (0.48) | BACE1PTGER1PTGER3PTGER2GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090258835-A1 | COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA TEC EDMONTON (CA) | 2009-10-15 | — | — | US | claimed |
| US-7524885-B2 | Compounds that stimulate glucose utilization and methods of use | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2009-04-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258835-A1 | COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE | GPR119, SLC2A4, SLC2A1 | FFAR4 263/4885BACE1 2986/4885SLC6A11 3227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.