Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1594471 | 0.87 | APP (0.46) | CYP3A4MAPTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL20442778 | 0.87 | KDM4E (0.46) | MAPTKDM4ELMNAL3MBTL1ALDH1A1 | |
| SCHEMBL16380530 | 0.87 | L3MBTL1 (0.47) | PPARAMAPTKDM4ELMNAL3MBTL1 | |
| SCHEMBL1594876 | 0.86 | CA12 (0.40) | MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL21348713 | 0.86 | APP (0.48) | MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL31410107 | 0.86 | APP (0.48) | MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL25222743 | 0.85 | APP (0.43) | MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL18858804 | 0.85 | PKM (0.46) | PPARAMAPTKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL28879763 | 0.85 | L3MBTL1 (0.49) | PPARAMAPTKDM4ELMNAL3MBTL1 | |
| SCHEMBL25252447 | 0.85 | ALDH1A1 (0.45) | PPARAMAPTKDM4ELMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051909-A1 | COMPOUNDS HAVING ACTIVITY IN CORRECTING MUTANT-CFTR CELLULAR PROCESSING AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-04-23 | — | — | WO | disclosed |