⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25340335 | 0.97 | LMNA (0.55) | — | |
| SCHEMBL96264 | 0.84 | CA12 (0.46) | — | |
| SCHEMBL28912905 | 0.84 | ALDH1A1 (0.46) | — | |
| SCHEMBL5143938 | 0.80 | CA12 (0.57) | — | |
| SCHEMBL11082586 | 0.78 | LMNA (0.38) | — | |
| SCHEMBL139066 | 0.78 | — | — | |
| SCHEMBL2097527 | 0.78 | LMNA (0.60) | — | |
| SCHEMBL6244448 | 0.78 | — | — | |
| SCHEMBL2327551 | 0.78 | LMNA (0.78) | — | |
| SCHEMBL6539776 | 0.77 | ALDH1A1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 439 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250114457-A1 | PHARMACEUTICAL COMPOSITIONS OF FUMARIC ACID ESTERS | HPS INVESTMENT PARTNERS, LLC, AS ADMINISTRATIVE AGENT | 2025-04-10 | — | — | US | claimed |
| CN-116875389-A | Leavening agent and preparation method, application and application method thereof | 深圳市贝加电子材料有限公司 | 2023-10-13 | — | — | CN | claimed |
| US-20220241420-A1 | Pharmaceutical Compositions of Fumaric Acid Esters | ARBOR PHARMACEUTICALS, LLC | 2022-08-04 | — | — | US | claimed |
| US-11135296-B2 | Pharmaceutical compositions of fumaric acid esters | ARBOR PHARMACEUTICALS, LLC (US) | 2021-10-05 | — | — | US | claimed |
| US-20190117776-A1 | Pharmaceutical Compositions of Fumaric Acid Esters | HPS INVESTMENT PARTNERS, LLC, AS ADMINISTRATIVE AGENT | 2019-04-25 | — | — | US | claimed |
| US-9999672-B2 | Pharmaceutical compositions of fumaric acid esters | XENOPORT, INC. (US) | 2018-06-19 | — | — | US | claimed |
| US-20150265707-A1 | PHARMACEUTICAL COMPOSITIONS OF FUMARIC ACID ESTERS | HPS INVESTMENT PARTNERS, LLC, AS ADMINISTRATIVE AGENT | 2015-09-24 | — | — | US | claimed |
| EP-2488524-B1 | PYRROLO[2,3-D]PYRIMIDINE COMPOUNDS | PFIZER (US) | 2013-07-03 | — | — | EP | claimed |
| US-20120226036-A1 | SUBSTITUTED CARBONYL COMPOUND | UBE INDUSTRIES, LTD. (JP) | 2012-09-06 | — | — | US | claimed |
| EP-2488524-A1 | PYRROLO[2,3-D]PYRIMIDINE COMPOUNDS | Pfizer Inc. (US) | 2012-08-22 | — | — | EP | claimed |
| EP-0950657-B1 | Substituted carbazoles, process for their preparation and their use as sPLA2 inhibitors | LILLY CO ELI (US) | 2004-07-14 | — | — | EP | claimed |
| EP-0952149-B1 | Substituted carbazoles, process for their preparation and their use as sPLA2 inhibitiors | LILLY CO ELI (US) | 2004-06-09 | — | — | EP | claimed |
| WO-2004041201-A2 | BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES | VIROPHARMA INCORPORATED (US) | 2004-05-21 | — | — | WO | claimed |
| EP-1156050-B1 | Substituted tricyclics useful in sPLA2 induced diseases | LILLY CO ELI (US) | 2004-02-18 | — | — | EP | claimed |
| WO-2003093244-A1 | SUBSTITUTED (THIOXO)CARBONYLAMINO PHENYL URACILES | BAYER CROPSCIENCE AG (DE) | 2003-11-13 | — | — | WO | claimed |
| EP-1140943-B1 | SUBSTITUTED PYRROLOINDOLES | LILLY CO ELI (US) | 2003-08-13 | — | — | EP | claimed |
| EP-0832082-A1 | N-HETEROARYL-PYRIDINESULFONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ZENECA LIMITED (GB) | 1998-04-01 | — | — | EP | claimed |
| WO-1996040681-A1 | N-HETEROARYL-PYRIDINESULFONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ZENECA LIMITED (GB) | 1996-12-19 | — | — | WO | claimed |
| US-4455428-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1984-06-19 | — | — | US | claimed |
| US-4119777-A | BY OXIDATION OF A THIOAMIDE DERIVATIVE | FUJI PHOTO FILM CO., LTD. (JP) | 1978-10-10 | — | — | US | claimed |