SCHEMBL408424

SCHEMBL408424

O=C(O)/C=C/C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL239930 1.00
SCHEMBL17186622 1.00
Ethane SCHEMBL7650344 0.94 TSHR (0.42)
SCHEMBL5598957 0.80 CYP1A2 (0.36)
SCHEMBL899316 0.79 TSHR (0.44)
SCHEMBL27138000 0.79
SCHEMBL899318 0.79 TSHR (0.44)
SCHEMBL3102115 0.77
SCHEMBL16506925 0.77
SCHEMBL17275146 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 578 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110093061-B Photosensitive resin with maleimide structure and preparation method and application thereof 浙江永太新材料有限公司 2022-04-22 CN claimed
CN-109385150-B Waterproof weather-resistant double-component exterior wall emulsion paint 广东彩居建筑工程有限公司 2021-04-16 CN claimed
WO-2020148780-A1 PROCESS FOR PREPARATION OF 4,4,4- TRIFLUOROBUT-2-EN-1-OL AND INTERMEDIATE THEREOF SRF LIMITED (IN) 2020-07-23 WO claimed
EP-1044991-B1 Process of preparing curable compositions and compositions therefrom ROHM & HAAS (US) 2004-02-11 EP claimed
JP-11158145-A None JP disclosed
US-20260137666-A1 N-methyl-D-aspartic Acid Receptor Modulators EMORY UNIV (US) 2026-05-21 US disclosed
US-12612414-B2 Nitrile SUMO inhibitors and uses thereof CIT THERAPEUTICS, INC. (US) 2026-04-28 US disclosed
US-12552798-B2 Substituted imidazolecarboxamide as Bruton's tyrosine kinase inhibitors HENAN ZHIWEI BIOMEDICINE CO., LTD. (CN) 2026-02-17 US disclosed
US-12544363-B2 N-methyl-D-aspartic acid receptor modulators EMORY UNIVERISTY (US) 2026-02-10 US disclosed
US-20250353854-A1 FUSED PYRIMIDINE COMPOUNDS AS INHIBITORS OF MENIN BIOMEA FUSION INC (US) 2025-11-20 US disclosed
EP-4116302-B1 COMPOUND AND PREPARATION METHOD THEREOF AND APPLICATION THEREOF IN PREPARATION OF THERAPEUTIC ANTI-CANCER DRUG TIANJIN JIKUN MEDICAL TECH CO LTD (CN) 2025-10-29 EP disclosed
US-12398151-B2 Sumo inhibitor compounds and uses thereof Suvalent Therapeutics, Inc. (US) 2025-08-26 US disclosed
US-5679832-A Method for making α,β-unsaturated-β-trifluoromethyl-carboxylates and related compounds ROHM AND HAAS COMPANY (US) 1997-10-21 US disclosed
US-5665759-A ADMINISTERING A NITROPYRROLE OR PYRROLE CARBONITRILE COMPOUND AMERICAN CYANAMID COMPANY (US) 1997-09-09 US disclosed
EP-0768296-A1 A method for making alpha, beta-unsaturated-beta-trifluoromethyl-carboxylates ROHM AND HAAS COMPANY (US) 1997-04-16 EP disclosed
US-5371239-A Pyrrole nitrile or nitropyrrole compounds AMERICAN CYANAMID COMPANY (US) 1994-12-06 US disclosed
US-5204332-A PYRROLE CARBONITRILE AND NITROPYRROLE INSECTICIDAL AND ACARICIDAL AND MOLLUSCICIDAL AGENTS AMERICAN CYANAMID COMPANY (US) 1993-04-20 US disclosed
US-5162308-A Pyrrole carbonitrile and nitropyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof AMERICAN CYANAMID COMPANY (US) 1992-11-10 US disclosed
US-4241076-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1980-12-23 US disclosed
US-4154935-A Halogen substituted mercaptoacylamino acids E. R. SQUIBB & SONS, INC. (US) 1979-05-15 US disclosed