Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL206885 | 0.86 | OPRM1 (0.41) | OPRM1OPRL1MAPTTP53ICMT | |
| SCHEMBL4084421 | 0.84 | OPRM1 (0.45) | OPRM1OPRL1ALDH1A1MAPTTP53 | |
| SCHEMBL4074077 | 0.82 | OPRM1 (0.51) | OPRM1OPRL1NPC1RAB9A | |
| SCHEMBL205762 | 0.82 | OPRM1 (0.46) | OPRM1OPRL1ALDH1A1MAPTKMT2A | |
| SCHEMBL4084259 | 0.80 | OPRM1 (0.38) | OPRM1OPRL1ALDH1A1MAPTTP53 | |
| SCHEMBL4074080 | 0.79 | OPRM1 (0.51) | OPRM1OPRL1NPC1RAB9A | |
| SCHEMBL4079677 | 0.78 | OPRM1 (0.47) | OPRM1OPRL1NPC1RAB9A | |
| SCHEMBL4079674 | 0.75 | OPRM1 (0.45) | OPRM1OPRL1NPC1RAB9A | |
| SCHEMBL4079669 | 0.75 | OPRM1 (0.45) | OPRM1OPRL1ALDH1A1NPC1RAB9A | |
| SCHEMBL250636 | 0.74 | LTA4H (0.52) | ALDH1A1MAPTKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | claimed |