SCHEMBL2114169

SCHEMBL2114169

Nc1ccc2c(S(=O)(=O)O)c(S(=O)(=O)O)ccc2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 4/20 0.51
NSD2 O96028 2/20 0.51
NT5E P21589 2/20 0.51
DUSP3 P51452 1/20 0.51
PTPN5 P54829 1/20 0.51
PTPN11 Q06124 1/20 0.51
RAPGEF4 Q8WZA2 1/20 0.44
PLAU P00749 1/20 0.43
ALDH1A1 P00352 7/20 0.42
HSD17B10 Q99714 4/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
TDP1 Q9NUW8 3/20 0.41
RECQL P46063 3/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
KDM4E B2RXH2 2/20 0.41
POLB P06746 2/20 0.41
GAA P10253 2/20 0.41
MAPT P10636 2/20 0.41
APEX1 P27695 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9334347 0.89 NT5E (0.56) CASP6NSD2NT5EDUSP3PTPN5
SCHEMBL9354745 0.87 CASP6 (0.50) CASP6NSD2NT5EDUSP3PTPN5
SCHEMBL4084347 0.86 CASP6 (0.57) CASP6NSD2NT5EDUSP3PTPN5
SCHEMBL6051234 0.85 CASP6 (0.51) CASP6NSD2NT5EDUSP3PTPN5
SCHEMBL5028738 0.84 CASP6 (0.54) CASP6NSD2NT5EDUSP3PTPN5
SCHEMBL2469761 0.82 CASP6 (0.51) CASP6NSD2NT5EDUSP3PTPN5
SCHEMBL27519146 0.80 NT5E (0.54) CASP6NSD2NT5EDUSP3PTPN5
SCHEMBL7511717 0.80 RAPGEF4 (0.56) CASP6NSD2NT5EDUSP3PTPN5
SCHEMBL29215781 0.79 CASP6 (0.57) CASP6NSD2NT5EDUSP3PTPN5
SCHEMBL6559611 0.79 NT5E (0.57) CASP6NSD2NT5EDUSP3PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170283733-A1 DISPERSANT VISCOSITY MODIFIERS WITH SULFONATE FUNCTIONALITY THE LUBRIZOL CORPORATION 2017-10-05 US claimed
EP-3209756-A1 DISPERSANT VISCOSITY MODIFIERS WITH SULFONATE FUNCTIONALITY The Lubrizol Corporation (US) 2017-08-30 EP claimed
WO-2016044262-A1 DISPERSANT VISCOSITY MODIFIERS WITH SULFONATE FUNCTIONALITY THE LUBRIZOL CORPORATION (US) 2016-03-24 WO claimed
US-20170283733-A1 DISPERSANT VISCOSITY MODIFIERS WITH SULFONATE FUNCTIONALITY THE LUBRIZOL CORPORATION 2017-10-05 US disclosed
EP-3209756-A1 DISPERSANT VISCOSITY MODIFIERS WITH SULFONATE FUNCTIONALITY The Lubrizol Corporation (US) 2017-08-30 EP disclosed
CN-102566269-B Coloured composition, colour filter and display element JSR株式会社 2016-06-15 CN disclosed
WO-2016044262-A1 DISPERSANT VISCOSITY MODIFIERS WITH SULFONATE FUNCTIONALITY THE LUBRIZOL CORPORATION (US) 2016-03-24 WO disclosed
CN-102116890-B Polarizing film NITTO DENKO CORP 2013-06-05 CN disclosed
US-8158022-B2 Polarizing film NITTO DENKO CORPORATION (JP) 2012-04-17 US disclosed
US-20110163268-A1 POLARIZING FILM NITTO DENKO CORPORATION (JP) 2011-07-07 US disclosed
CN-102116890-A Polarizing film NITTO DENKO CORP 2011-07-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110163268-A1 POLARIZING FILM CRY1, PYM1, NPM1 CASP6 2282/4885NSD2 994/4885NT5E 2426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.