Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.35 |
| ▸ | STK10 | O94804 | 2/20 | 0.34 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19089973 | 0.97 | FADS1 (0.40) | FADS1CDC25BALDH1A1TP53CYP3A4 | |
| SCHEMBL231250 | 0.90 | CDC25B (0.53) | FADS1CDC25BALDH1A1TP53CYP3A4 | |
| SCHEMBL24890009 | 0.89 | FADS1 (0.40) | FADS1CDC25BALDH1A1TP53CYP3A4 | |
| SCHEMBL12249879 | 0.89 | FADS1 (0.49) | FADS1CDC25BALDH1A1TP53CYP3A4 | |
| SCHEMBL29514742 | 0.89 | FADS1 (0.49) | FADS1CDC25BALDH1A1TP53CYP3A4 | |
| SCHEMBL13907827 | 0.86 | FADS1 (0.47) | FADS1CDC25BALDH1A1TP53CYP3A4 | |
| SCHEMBL25124813 | 0.86 | CDC25B (0.39) | FADS1CDC25BALDH1A1TP53CYP3A4 | |
| SCHEMBL17733224 | 0.85 | CDC25B (0.39) | FADS1CDC25BALDH1A1TP53CYP3A4 | |
| SCHEMBL25124788 | 0.84 | CDC25B (0.38) | FADS1CDC25BALDH1A1TP53CYP3A4 | |
| SCHEMBL22517374 | 0.84 | ALDH1A1 (0.37) | FADS1CDC25BALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2006278-B2 | BENZOFLUORENE COMPOUND AND USE THEREOF | TOSOH CORP (JP) | 2016-10-12 | — | — | EP | disclosed |
| US-8993805-B2 | Benzofluorene compound and use thereof | TOSOH CORPORATION (JP) | 2015-03-31 | — | — | US | disclosed |
| EP-2006278-B1 | BENZOFLUORENE COMPOUND AND USE THEREOF | TOSOH CORP (JP) | 2012-12-26 | — | — | EP | disclosed |
| EP-2006278-A9 | BENZOFLUORENE COMPOUND AND USE THEREOF | Tosoh Corporation (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-20090184312-A1 | BENZOFLUORENE COMPOUND AND USE THEREOF | TOSOH CORPORATION (JP) | 2009-07-23 | — | — | US | disclosed |
| EP-2006278-A2 | BENZOFLUORENE COMPOUND AND USE THEREOF | Tosoh Corporation (JP) | 2008-12-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090184312-A1 | BENZOFLUORENE COMPOUND AND USE THEREOF | SLC7A1, SLC43A1, SLC7A5 | FADS1 3090/4885CDC25B 4176/4885ALDH1A1 1932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.