SCHEMBL4084643

SCHEMBL4084643

CCCCCCC(C)NC

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 1/20 0.56
ADH1C P00326 1/20 0.56
ADH1A P07327 1/20 0.56
ADH4 P08319 1/20 0.56
ADH7 P40394 1/20 0.56
OPRM1 P35372 1/20 0.46
SPHK1 Q9NYA1 1/20 0.43
LMNA P02545 1/20 0.42
TSHR P16473 1/20 0.42
THRB P10828 1/20 0.42
DNM1 Q05193 2/20 0.42
EPHX1 P07099 1/20 0.42
ACE2 Q9BYF1 1/20 0.39
FDPS P14324 3/20 0.38
GPR84 Q9NQS5 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9863341 1.00 ADH1B (0.56) ADH1BADH1CADH1AADH4ADH7
SCHEMBL871690 1.00 ADH1B (0.56) ADH1BADH1CADH1AADH4ADH7
SCHEMBL6898195 1.00 ADH1B (0.56) ADH1BADH1CADH1AADH4ADH7
SCHEMBL23340664 1.00 ADH1B (0.56) ADH1BADH1CADH1AADH4ADH7
SCHEMBL8571264 1.00 ADH1B (0.56) ADH1BADH1CADH1AADH4ADH7
SCHEMBL24631739 1.00 ADH1B (0.56) ADH1BADH1CADH1AADH4ADH7
SCHEMBL668931 1.00 ADH1B (0.56) ADH1BADH1CADH1AADH4ADH7
SCHEMBL11851660 1.00 ADH1B (0.56) ADH1BADH1CADH1AADH4ADH7
SCHEMBL9203991 1.00 ADH1B (0.56) ADH1BADH1CADH1AADH4ADH7
SCHEMBL6269026 1.00 ADH1B (0.56) ADH1BADH1CADH1AADH4ADH7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110669058-A Tricyclic quinolone carboxylic acid and preparation method thereof 江西农业大学 2020-01-10 CN claimed
WO-2024050352-A2 Branched Lipid Compositions, Lipid Nanoparticles (LNPs) Comprising the Same, and Methods of Use Thereof THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2024-03-07 WO disclosed
WO-2023211938-A1 METHODS OF USING A (THIAZOLYL)BENZENESULFONAMIDE DERIVATIVE CYTEIR THERAPEUTICS, INC. (US) 2023-11-02 WO disclosed
US-11702432-B2 Method of making an organoaminosilane DOW SILICONES CORPORATION (US) 2023-07-18 US disclosed
US-20230036244-A1 NON-FLAMMABLE POLYMERIC ELECTROLYTE WITH WIDE OPERATIONAL TEMPERATURE RANGE THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2023-02-02 US disclosed
EP-3400255-B1 PROCESS FOR PREPARING GRAFT COPOLYMER COMPRISING POLYETHYLENE SABIC GLOBAL TECHNOLOGIES BV (NL) 2022-04-20 EP disclosed
EP-3390410-B1 METHODS OF MAKING HIGH PURITY TRISILYLAMINE NATA SEMICONDUCTOR MAT CO LTD (CN) 2022-02-02 EP disclosed
WO-2022015656-A1 CAMPTOTHECIN ANALOGS CONJUGATED TO A GLUTAMINE RESIDUE IN A PROTEIN, AND THEIR USE REGENERON PHARMACEUTICALS, INC. (US) 2022-01-20 WO disclosed
US-11111256-B2 High purity trisilylamine, methods of making, and use JIANGSU NATA OPTO-ELECTRONIC MATERIALS CO. LTD. (CN) 2021-09-07 US disclosed
CN-108602839-B A process for preparing an organoaminosilane; method for producing silylamines from organoaminosilanes 南大光电半导体材料有限公司 2021-06-29 CN disclosed
CN-110669058-A Tricyclic quinolone carboxylic acid and preparation method thereof 江西农业大学 2020-01-10 CN disclosed
US-20190352315-A1 METHOD FOR MAKING AN ORGANOAMINOSILANE; A METHOD FOR MAKING A SILYLAMINE FROM THE ORGANOAMINOSILANE DOW SILICONES CORPORATION (US) 2019-11-21 US disclosed
EP-3390411-A1 METHOD FOR MAKING AN ORGANOAMINOSILANE; A METHOD FOR MAKING A SILYLAMINE FROM THE ORGANOAMINOSILANE Dow Corning Corporation (US) 2018-10-24 EP disclosed
EP-3390410-A1 HIGH PURITY TRISILYLAMINE, METHODS OF MAKING, AND USE Dow Corning Corporation (US) 2018-10-24 EP disclosed
US-20170291885-A1 METHOD FOR PREPARING ENAMIDE COMPOUND AND RUTHENIUM COMPLEX CATALYST USED THEREIN POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2017-10-12 US disclosed
WO-2017106632-A1 METHOD FOR MAKING AN ORGANOAMINOSILANE; A METHOD FOR MAKING A SILYLAMINE FROM THE ORGANOAMINOSILANE DOW CORNING CORPORATION (US) 2017-06-22 WO disclosed
WO-2017106625-A1 HIGH PURITY TRISILYLAMINE, METHODS OF MAKING, AND USE DOW CORNING CORPORATION (US) 2017-06-22 WO disclosed
US-20160130282-A1 MERCAPTOAMIDINE DERIVATIVES AND METHODS OF USE ABBVIE INC. 2016-05-12 US disclosed
WO-2014086751-A1 USE OF SUBSTITUTED 1-(ARYL ETHYNYL)-, 1-(HETEROARYL ETHYNYL)-, 1-(HETEROCYCLYL ETHYNYL)- AND 1-(CYLOALKENYL ETHYNYL)-CYCLOHEXANOLS AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2014-06-12 WO disclosed
US-20090180914-A1 Interconnect material and interconnect formation method HITACHI, LTD. 2009-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160130282-A1 MERCAPTOAMIDINE DERIVATIVES AND METHODS OF USE HNMT, HRH2, HRH4 ADH1B 429/4885ADH1C 262/4885ADH1A 356/4885
US-20170291885-A1 METHOD FOR PREPARING ENAMIDE COMPOUND AND RUTHENIUM COMPLEX CATALYST USED THEREIN ENY2, ENO1, IDH1 ADH1B 245/4885ADH1C 922/4885ADH1A 710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.