SCHEMBL408489

SCHEMBL408489

CCCCCCCC[SiH2]O[Si](C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.38
THRB P10828 1/20 0.38
DNM1 Q05193 7/20 0.31
ALDH1A1 P00352 3/20 0.31
LMNA P02545 2/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
HSD17B10 Q99714 1/20 0.31
SLC22A1 O15245 1/20 0.31
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1694297 1.00 TSHR (0.38) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL28290062 0.98 TSHR (0.33) TSHRTHRB
SCHEMBL13714367 0.90 LMNA (0.30) TSHRLMNA
SCHEMBL16589230 0.86 TSHR (0.50) TSHRALDH1A1EPHX1
Tromethamine SCHEMBL7453417 0.84 S1PR1 (0.37) LMNAMEN1KMT2A
SCHEMBL31344505 0.79 TSHR (0.36) TSHRTHRB
SCHEMBL6035908 0.79 TSHR (0.36) TSHRTHRBALDH1A1
SCHEMBL10723520 0.77 TSHR (0.35) TSHRTHRB
SCHEMBL4828707 0.77 TSHR (0.35) TSHRTHRBLMNA
SCHEMBL6907485 0.77 TSHR (0.35) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111902738-B Naphthalene-based high refractive index hydrophobic liquid and transmittance restorative for liquid lens formulation 康宁股份有限公司 2023-06-16 CN claimed
CN-119866458-A Polyfluoroaromatic derivatives for liquid lenses 康宁股份有限公司 2025-04-22 CN disclosed
CN-111902738-B Naphthalene-based high refractive index hydrophobic liquid and transmittance restorative for liquid lens formulation 康宁股份有限公司 2023-06-16 CN disclosed
US-20220320682-A1 COMPOSITE SEPARATOR FOR LITHIUM SECONDARY BATTERY AND MANUFACTURING THE SAME G-MATERIALS CO.,LTD. (KR) 2022-10-06 US disclosed
EP-4020657-A1 COMPOSITE SEPARATOR FOR LITHIUM SECONDARY BATTERY, AND MANUFACTURING METHOD THEREFOR G-Materials Co.,Ltd. (KR) 2022-06-29 EP disclosed
EP-2411450-B1 A PARTICLE CONTAINING A HYDROPHOBIC REGION AND A HYDROPHILIC REGION AND METHODS TO MAKE SAME CABOT CORP (US) 2018-12-26 EP disclosed
EP-2411450-A1 A PARTICLE CONTAINING A HYDROPHOBIC REGION AND A HYDROPHILIC REGION AND METHODS TO MAKE SAME Cabot Corporation (US) 2012-02-01 EP disclosed
US-20120020106-A1 PARTICLE CONTAINING A HYDROPHOBIC REGION AND A HYDROPHILIC REGION AND METHODS TO MAKE SAME CABOT CORPORATION (US) 2012-01-26 US disclosed
WO-2010110852-A1 A PARTICLE CONTAINING A HYDROPHOBIC REGION AND A HYDROPHILIC REGION AND METHODS TO MAKE SAME CABOT CORPORATION (US) 2010-09-30 WO disclosed
EP-2231758-A1 FILLER SYSTEM INCLUDING DENSED FUMED METAL OXIDE Cabot Corporation (US) 2010-09-29 EP disclosed
WO-2009082416-A1 FILLER SYSTEM INCLUDING DENSED FUMED METAL OXIDE CABOT CORPORATION (US) 2009-07-02 WO disclosed
US-20090163637-A1 Filler system including densed fumed metal oxide CABOT CORPORATION 2009-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120020106-A1 PARTICLE CONTAINING A HYDROPHOBIC REGION AND A HYDROPHILIC REGION AND METHODS TO MAKE SAME HNRNPF, PUM1, FUS TSHR 4046/4885THRB 4281/4885DNM1 4213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.