SCHEMBL28290062

SCHEMBL28290062

CCCCC[SiH2]O[Si](C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL408489 0.98 TSHR (0.38) TSHRTHRB
SCHEMBL1694297 0.98 TSHR (0.38) TSHRTHRB
SCHEMBL13714367 0.92 LMNA (0.30) TSHR
SCHEMBL16589230 0.83 TSHR (0.50) TSHR
Tromethamine SCHEMBL7453417 0.82 S1PR1 (0.37)
SCHEMBL2030789 0.77 NFKB1 (0.30)
SCHEMBL9810808 0.76 TSHR (0.30) TSHRTHRB
SCHEMBL31344505 0.76 TSHR (0.36) TSHRTHRB
SCHEMBL6035908 0.76 TSHR (0.36) TSHRTHRB
SCHEMBL8013483 0.76 TSHR (0.30) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109641482-A The preparation of the cis- -1,4- polydiene of multiple silane functionals with the Si―H addition reaction in situ preparation by polymer glue 株式会社普利司通 2019-04-16 CN disclosed