SCHEMBL13714367

SCHEMBL13714367

CCCC[SiH2]O[Si](C)(C)C

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28290062 0.92 TSHR (0.33) TSHR
SCHEMBL408489 0.90 TSHR (0.38) LMNATSHR
SCHEMBL6679394 0.84 TSHR (0.42) TSHR
SCHEMBL17735797 0.81
SCHEMBL2030789 0.79 NFKB1 (0.30)
SCHEMBL6904964 0.77
SCHEMBL9810768 0.75
SCHEMBL28290074 0.73
SCHEMBL9390318 0.72 TSHR (0.37) TSHR
SCHEMBL9840435 0.71 TSHR (0.38) LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117280252-A Multifocal diffractive silicone hydrogel contact lenses 爱尔康公司 2023-12-22 CN claimed
CN-115605529-B Photochromic polydiorganosiloxane vinyl cross-linking agent 爱尔康公司 2024-03-26 CN disclosed
CN-114502362-B Contact lenses with surfaces of different softness 爱尔康公司 2024-03-26 CN disclosed
CN-114981072-B Wettable silicone hydrogel contact lenses 爱尔康公司 2024-03-26 CN disclosed
CN-117492231-A Zhou Pao and month polishing gradient contact lens 爱尔康公司 2024-02-02 CN disclosed
CN-117492228-A Zhou Pao and month polishing gradient contact lens 爱尔康公司 2024-02-02 CN disclosed
CN-117492232-A Zhou Pao and month polishing gradient contact lens 爱尔康公司 2024-02-02 CN disclosed
CN-117492230-A Zhou Pao and month polishing gradient contact lens 爱尔康公司 2024-02-02 CN disclosed
CN-117492229-A Zhou Pao and month polishing gradient contact lens 爱尔康公司 2024-02-02 CN disclosed
CN-117280252-A Multifocal diffractive silicone hydrogel contact lenses 爱尔康公司 2023-12-22 CN disclosed
CN-111386478-B Zhou Pao and month polishing gradient contact lens 爱尔康公司 2023-11-14 CN disclosed
CN-111919141-B Silicone Hydrogel Contact Lenses 爱尔康公司 2023-11-14 CN disclosed
CN-116867836-A Hydrophilized polydiorganosiloxane vinyl cross-linking agent 爱尔康公司 2023-10-10 CN disclosed
CN-109690360-B Method for producing contact lenses having durable lubricious coatings thereon 爱尔康公司 2023-04-25 CN disclosed
CN-108755264-A Glass plate lining paper wood pulp and glass plate lining paper 特种东海制纸株式会社 2018-11-06 CN disclosed
CN-107075814-A Wood pulp for glass plate lining paper and lining paper for glass plate 特种东海制纸株式会社 2017-08-18 CN disclosed
US-7576231-B2 Method for producing isocyanate group-containing siloxane compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-08-18 US disclosed
US-20080183001-A1 Method for producing isocyanate group-containing siloxane compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-07-31 US disclosed
CN-1301795-C Photocatalyst composition ASAHI CHEMICAL IND (JP) 2007-02-28 CN disclosed
CN-1638868-A Photocatalyst composition ASAHI CHEMICAL IND (JP) 2005-07-13 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080183001-A1 Method for producing isocyanate group-containing siloxane compound OR10J3, OXSR1, CBR3 LMNA 1941/4885TSHR 973/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.