Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4632472 | 0.83 | CHRNB2 (0.43) | LMNASLC6A2SLC6A3 | |
| SCHEMBL4361544 | 0.81 | LMNA (0.45) | ALOX5FFAR1PTGS1PTGS2LMNA | |
| SCHEMBL902225 | 0.81 | SLC6A2 (0.56) | LMNASLC6A2SLC6A3 | |
| SCHEMBL4967524 | 0.81 | SLC6A2 (0.56) | LMNASLC6A2SLC6A3 | |
| SCHEMBL2761798 | 0.81 | SLC6A2 (0.56) | LMNASLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL4739317 | 0.80 | SLC6A2 (0.56) | LMNASLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL3349919 | 0.80 | SLC6A2 (0.56) | LMNASLC6A2SLC6A3 | |
| SCHEMBL8028820 | 0.79 | SLC6A2 (0.52) | PTGS1LMNACYP1A2SLC6A2CYP2C19 | |
| SCHEMBL902452 | 0.79 | SLC6A2 (0.52) | PTGS1LMNACYP1A2SLC6A2CYP2C19 | |
| SCHEMBL8028845 | 0.79 | SLC6A2 (0.52) | PTGS1LMNACYP1A2SLC6A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009010990-A2 | PROCESS FOR THE PREPARATION OF O-DESMETHYLVENLAFAXINE SUCCINATE POLYMORPHIC FORMS | MATRIX LABORATORIES LIMITED (IN) | 2009-01-22 | — | — | WO | disclosed |