Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4084407 | 0.87 | L3MBTL1 (0.40) | L3MBTL1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL206832 | 0.84 | EPHX2 (0.45) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4081367 | 0.81 | EPHX2 (0.35) | L3MBTL1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL205941 | 0.81 | MEN1 (0.42) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL206771 | 0.80 | AR (0.46) | TSHR | |
| SCHEMBL207812 | 0.80 | MAPT (0.48) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL205977 | 0.79 | L3MBTL1 (0.39) | L3MBTL1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL206085 | 0.79 | ALDH1A1 (0.48) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL209123 | 0.79 | GFER (0.54) | L3MBTL1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL206152 | 0.79 | POLB (0.37) | L3MBTL1MEN1KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | claimed |