Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL206832 | 0.90 | EPHX2 (0.45) | EPHX2ALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL4084407 | 0.84 | L3MBTL1 (0.40) | EPHX2ALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL4085357 | 0.81 | L3MBTL1 (0.38) | ALDH1A1L3MBTL1KMT2AMEN1CYP2C19 | |
| SCHEMBL206771 | 0.80 | AR (0.46) | — | |
| SCHEMBL209123 | 0.79 | GFER (0.54) | ALDH1A1L3MBTL1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL208978 | 0.79 | RAB9A (0.48) | ALDH1A1KMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL207812 | 0.79 | MAPT (0.48) | ALDH1A1KMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL205977 | 0.78 | L3MBTL1 (0.39) | EPHX2ALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL205941 | 0.78 | MEN1 (0.42) | ALDH1A1KMT2AMEN1CYP2C19SMN1; SMN2 | |
| SCHEMBL206085 | 0.78 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | claimed |
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | disclosed |