Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.43 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4086023 | 0.81 | HSD17B1 (0.64) | MEN1KMT2ASRD5A2HSD17B1 | |
| SCHEMBL12325012 | 0.78 | HSD17B1 (0.59) | MAPTLMNAKDM4EHSD17B1 | |
| SCHEMBL4085532 | 0.75 | KDM4E (0.60) | ABCG2KMT2AHSP90AA1DNMT1KDM4E | |
| SCHEMBL4085995 | 0.75 | SMN1; SMN2 (0.54) | MEN1KMT2AMAPTLMNASRD5A2 | |
| SCHEMBL23137322 | 0.74 | ALDH1A1 (0.50) | MEN1KMT2AHSP90AA1MAPTLMNA | |
| SCHEMBL23137323 | 0.74 | ALDH1A1 (0.50) | MEN1KMT2AHSP90AA1MAPTLMNA | |
| SCHEMBL4095528 | 0.74 | ALDH1A1 (0.43) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL4098160 | 0.73 | SRD5A2 (0.44) | MEN1KMT2AMAPTSRD5A2HSD17B1 | |
| SCHEMBL4455774 | 0.72 | HSD17B1 (0.43) | MEN1KMT2ASRD5A2HSD17B1 | |
| SCHEMBL4085538 | 0.72 | HSD17B1 (0.43) | MEN1KMT2AHSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090186900-A1 | COMPOUND | STERIX LIMITED (GB) | 2009-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186900-A1 | COMPOUND | HSD17B2, HSD17B11, CYP17A1 | ABCG2 1752/4885MEN1 1122/4885KMT2A 2145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.