Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | C1R | P00736 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759225 | 0.73 | GAA (0.44) | NPC1RAB9AMITFPKMLMNA | |
| SCHEMBL9689620 | 0.72 | NPC1 (0.54) | NPC1RAB9AMITFPKMMAPT | |
| SCHEMBL10044417 | 0.72 | NPC1 (0.62) | NPC1RAB9AMITFPKMLMNA | |
| Hydrochloric Acid SCHEMBL9689682 | 0.71 | NPC1 (0.53) | NPC1RAB9AMITFPKMMAPT | |
| SCHEMBL6216387 | 0.70 | NPC1 (0.64) | NPC1RAB9AMITFPKMLMNA | |
| SCHEMBL13861649 | 0.69 | NPC1 (0.59) | NPC1RAB9AMITFPKMLMNA | |
| SCHEMBL4078075 | 0.69 | SMN1; SMN2 (0.38) | NPC1RAB9AMITFLMNAPOLB | |
| SCHEMBL7862743 | 0.69 | NPC1 (0.62) | NPC1RAB9AMITFPKMLMNA | |
| SCHEMBL9870217 | 0.69 | NPC1 (0.62) | NPC1RAB9AMITFPKMLMNA | |
| SCHEMBL11611242 | 0.68 | NPC1 (0.57) | NPC1RAB9AMITFPKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051504-A1 | BENZO- AND PYRIDOPYRIDAZINONES WITH ANALGESIC AND ANTIINFLAMMATORY ACTIVITY | UNIWERSYTET LODSKI (PL) | 2009-04-23 | — | — | WO | disclosed |