Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.37 |
| ▸ | BRD7 | Q9NPI1 | 3/20 | 0.37 |
| ▸ | TAF1 | P21675 | 2/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.37 |
| ▸ | CECR2 | Q9BXF3 | 2/20 | 0.37 |
| ▸ | TDP2 | O95551 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | BPTF | Q12830 | 1/20 | 0.37 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | ATAD2B | Q9ULI0 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4085550 | 0.69 | NPC1 (0.46) | SMN1; SMN2MAPTTDP1KMT2AGAA | |
| SCHEMBL29965637 | 0.65 | ALDH1A1 (0.55) | SMN1; SMN2TSHRKMT2AALDH1A1LMNA | |
| SCHEMBL9303821 | 0.63 | PRKCB (0.40) | TDP1CYP2D6ALDH1A1 | |
| SCHEMBL30302189 | 0.63 | MAPT (0.54) | SMN1; SMN2MAPTTSHRKMT2AMEN1 | |
| SCHEMBL16658125 | 0.60 | BRD4 (0.65) | BRD9BRD7TAF1TGFBR1ACVR1 | |
| SCHEMBL16658140 | 0.59 | BRD9 (0.61) | BRD9BRD7TAF1TGFBR1ACVR1 | |
| SCHEMBL10090152 | 0.58 | CASP3 (0.58) | SMN1; SMN2MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL30648519 | 0.58 | CYP11B2 (0.47) | SMN1; SMN2TSHRKMT2AMEN1GAA | |
| SCHEMBL15440804 | 0.58 | HTT (0.67) | SMN1; SMN2TDP1KMT2AGAAALDH1A1 | |
| SCHEMBL21227726 | 0.58 | BRD9 (0.69) | SMN1; SMN2MAPTTSHRBRD9BRD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051504-A1 | BENZO- AND PYRIDOPYRIDAZINONES WITH ANALGESIC AND ANTIINFLAMMATORY ACTIVITY | UNIWERSYTET LODSKI (PL) | 2009-04-23 | — | — | WO | disclosed |