SCHEMBL4085842

SCHEMBL4085842

CC(=O)c1ccc(-c2ccc(O)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 4/20 1.00
MAPT P10636 4/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
LMNA P02545 3/20 0.56
RAB9A P51151 2/20 0.56
KMT2A Q03164 2/20 0.56
MEN1 O00255 1/20 0.56
ESR1 P03372 3/20 0.55
ESR2 Q92731 3/20 0.55
PDPK1 O15530 1/20 0.54
HPGD P15428 3/20 0.52
PKM P14618 1/20 0.52
HTT P42858 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.50
XDH P47989 1/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA3 P07451 1/20 0.50
TYR P14679 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21935943 0.93 HSD17B1 (0.87) HSD17B1MAPTSMN1; SMN2LMNARAB9A
SCHEMBL22365141 0.93 HSD17B1 (0.87) HSD17B1MAPTSMN1; SMN2LMNARAB9A
4-Hydroxyacetophenone SCHEMBL8934912 0.92 HSD17B1 (0.85) HSD17B1MAPTSMN1; SMN2LMNARAB9A
4-Hydroxyacetophenone SCHEMBL40866 0.92 HSD17B1 (0.85) HSD17B1MAPTSMN1; SMN2LMNARAB9A
4-Hydroxyacetophenone SCHEMBL27639603 0.90 HSD17B1 (0.81) HSD17B1MAPTSMN1; SMN2LMNARAB9A
4-Hydroxyacetophenone SCHEMBL28050008 0.90 HSD17B1 (0.81) HSD17B1MAPTSMN1; SMN2LMNARAB9A
4-Hydroxyacetophenone SCHEMBL8744798 0.90 HSD17B1 (0.81) HSD17B1MAPTSMN1; SMN2LMNARAB9A
4-Hydroxyacetophenone SCHEMBL9480590 0.90 HSD17B1 (0.81) HSD17B1MAPTSMN1; SMN2LMNARAB9A
4-Hydroxyacetophenone SCHEMBL31385561 0.90 HSD17B1 (0.81) HSD17B1MAPTSMN1; SMN2LMNARAB9A
4-Hydroxyacetophenone SCHEMBL28895846 0.90 HSD17B1 (0.81) HSD17B1MAPTSMN1; SMN2LMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115181269-B Preparation method of hyperbranched nano-pore alkynyl polyimide resin 中国航空工业集团公司济南特种结构研究所 2023-05-23 CN claimed
CN-115181269-A Preparation method of hyperbranched nanopore alkynyl polyimide resin 中国航空工业集团公司济南特种结构研究所 2022-10-14 CN claimed
JP-59137433-A None JP disclosed
JP-1213254-A None JP disclosed
CN-115215734-B Preparation method of 1- [4- (4-hydroxyphenyl) phenyl ] -1, 1-bis (4-hydroxyphenyl) ethane 辽宁靖帆新材料有限公司 2024-01-05 CN disclosed
EP-3464297-B1 PROCESS FOR PREPARATION OF ERIBULIN AND INTERMEDIATES THEREOF Dr Reddys Laboratories Ltd (IN) 2023-10-25 EP disclosed
CN-115181269-B Preparation method of hyperbranched nano-pore alkynyl polyimide resin 中国航空工业集团公司济南特种结构研究所 2023-05-23 CN disclosed
CN-115181269-B Preparation method of hyperbranched nano-pore alkynyl polyimide resin 中国航空工业集团公司济南特种结构研究所 2023-05-23 CN disclosed
CN-115215734-A Preparation method of 1- [4- (4-hydroxyphenyl) phenyl ] -1, 1-bis (4-hydroxyphenyl) ethane 辽宁靖帆新材料有限公司 2022-10-21 CN disclosed
CN-115181269-A Preparation method of hyperbranched nanopore alkynyl polyimide resin 中国航空工业集团公司济南特种结构研究所 2022-10-14 CN disclosed
CN-115181269-A Preparation method of hyperbranched nanopore alkynyl polyimide resin 中国航空工业集团公司济南特种结构研究所 2022-10-14 CN disclosed
EP-0178929-A1 Process for producing aromatic diols and their ester and ether derivatives CELANESE CORPORATION (US) 1986-04-23 EP disclosed
EP-0170483-A2 Process for producing acyloxy aromatic carboxylic acid CELANESE CORPORATION (US) 1986-02-05 EP disclosed
US-4568763-A Process for producing N-acyl-acyloxy aromatic amines CELANESE CORPORATION (US) 1986-02-04 US disclosed
US-4560789-A Process for producing 4-acetoxyacetanilide CELANESE CORPORATION (US) 1985-12-24 US disclosed
US-4524217-A Process for producing N-acyl-hydroxy aromatic amines CELANESE CORPORATION (US) 1985-06-18 US disclosed
US-4517354-A PROTECTIVE COATINGS PLASTICS ENGINEERING COMPANY (US) 1985-05-14 US disclosed
JP-S59137433-A NOVEL BIPHENYL COMPOUND TANIGAKI TEIICHI 1984-08-07 JP disclosed
US-4423063-A 2,4-Dioxo-4-substituted-1-butaoic acid derivatives useful in treating urinary track calcium oxalate lithiasis MERCK & CO., INC. (US) 1983-12-27 US disclosed
US-4337258-A ENZYME INHIBITOR MERCK & CO., INC. (US) 1982-06-29 US disclosed