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Uridine_Diphosphate

Uridine_Diphosphate

SCHEMBL4086028

C=C(O[C@@H]([C@H](O)[C@H](O)CO)[C@H](C=O)NC(C)=O)C(=O)O.O=c1ccn([C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.53

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Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ P2RY2 P41231 11/20 0.53
▸ P2RY6 Q15077 8/20 0.53
▸ P2RY4 P51582 7/20 0.53
▸ P2RY14 Q15391 7/20 0.53
▸ OGT O15294 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3997190 0.91 P2RY2 (0.49) P2RY2P2RY6P2RY4P2RY14OGT
Uridine_Diphosphate SCHEMBL404650 0.90 P2RY6 (0.61) P2RY2P2RY6P2RY4P2RY14OGT
Uridine_Diphosphate SCHEMBL15641170 0.90 P2RY6 (0.61) P2RY2P2RY6P2RY4P2RY14OGT
Uridine_Diphosphate SCHEMBL28093501 0.90 P2RY6 (0.61) P2RY2P2RY6P2RY4P2RY14OGT
Uridine_Diphosphate SCHEMBL3508085 0.90 P2RY6 (0.61) P2RY2P2RY6P2RY4P2RY14OGT
Pyruvate SCHEMBL11424485 0.87 P2RY2 (0.50) P2RY2P2RY6P2RY4P2RY14OGT
SCHEMBL555278 0.86 P2RY2 (0.52) P2RY2P2RY6P2RY4P2RY14OGT
SCHEMBL1519760 0.86 P2RY2 (0.52) P2RY2P2RY6P2RY4P2RY14OGT
Uridine_Diphosphate SCHEMBL27463201 0.85 P2RY6 (0.65) P2RY2P2RY6P2RY4P2RY14
SCHEMBL16672237 0.84 P2RY2 (0.56) P2RY2P2RY6P2RY4P2RY14OGT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090203726-A1 SUBSTITUTED TETRAHYDROQUINOLINES AS ANTIBACTERIAL AGENTS MAXTHERA INC. (US) 2009-08-13 — — US disclosed
US-20060287351-A1 Antibiotic cycloalkyltetrahydroquinoline derivatives BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2006-12-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060287351-A1 Antibiotic cycloalkyltetrahydroquinoline derivatives TREH, CFTR, NRDC P2RY2 4687/4885P2RY6 4567/4885P2RY4 4448/4885
US-20090203726-A1 SUBSTITUTED TETRAHYDROQUINOLINES AS ANTIBACTERIAL AGENTS NISCH, NDUFS3, SDHA P2RY2 4476/4885P2RY6 4379/4885P2RY4 3986/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.