Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727239 | 0.90 | ITGB3 (0.54) | HDAC8 | |
| SCHEMBL4081470 | 0.90 | ITGB3 (0.54) | HDAC8 | |
| SCHEMBL8213080 | 0.89 | KLK5 (0.48) | HDAC8 | |
| SCHEMBL4086307 | 0.89 | KLK5 (0.48) | HDAC8 | |
| SCHEMBL8203638 | 0.81 | — | — | |
| SCHEMBL8212218 | 0.79 | F2 (0.49) | — | |
| SCHEMBL8215211 | 0.79 | DPP4 (0.46) | — | |
| SCHEMBL4826858 | 0.78 | ITGB3 (0.50) | HDAC8 | |
| SCHEMBL14003050 | 0.78 | ITGB3 (0.50) | HDAC8 | |
| SCHEMBL4739863 | 0.78 | ACE (0.60) | HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008029217-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2008-03-13 | — | — | WO | disclosed |