SCHEMBL4086543

SCHEMBL4086543

N[C@H](C(=O)O)[C@@H](O)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.58
NR1I2 O75469 1/20 0.58
PTGS1 P23219 1/20 0.58
ADRA1A P35348 1/20 0.58
BLM P54132 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
ADRA2A P08913 1/20 0.56
ADRA2C P18825 1/20 0.56
HIF1A Q16665 1/20 0.56
KDM4E B2RXH2 1/20 0.56
MAPK1 P28482 1/20 0.54
ALDH1A1 P00352 1/20 0.54
ACHE P22303 1/20 0.51
DPP4 P27487 2/20 0.50
CYP2D6 P10635 1/20 0.50
SRC P12931 1/20 0.50
SLC1A3 P43003 1/20 0.47
SLC1A2 P43004 1/20 0.47
SLC1A1 P43005 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16816913 1.00 LMNA (0.58) LMNANR1I2PTGS1ADRA1ABLM
SCHEMBL17982719 1.00 LMNA (0.58) LMNANR1I2PTGS1ADRA1ABLM
SCHEMBL10535250 1.00 LMNA (0.58) LMNANR1I2PTGS1ADRA1ABLM
SCHEMBL8229978 1.00 LMNA (0.58) LMNANR1I2PTGS1ADRA1ABLM
SCHEMBL751652 1.00 LMNA (0.58) LMNANR1I2PTGS1ADRA1ABLM
SCHEMBL4728748 1.00 LMNA (0.58) LMNANR1I2PTGS1ADRA1ABLM
SCHEMBL210030 1.00 LMNA (0.58) LMNANR1I2PTGS1ADRA1ABLM
SCHEMBL8528068 1.00 LMNA (0.58) LMNANR1I2PTGS1ADRA1ABLM
SCHEMBL443815 1.00 LMNA (0.58) LMNANR1I2PTGS1ADRA1ABLM
Hydrochloric Acid SCHEMBL6946154 0.98 ALDH1A1 (0.57) LMNANR1I2PTGS1ADRA1ABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4679087-A1 BIOMARKER AND USE THEREOF MEIJI CO., LTD (JP) 2026-01-14 EP claimed
WO-2024190663-A1 BIOMARKER AND USE THEREOF 株式会社明治 2024-09-19 WO claimed
US-4710583-A ENZYMATIC COUPLING OF PHENYLSERINE WITH ASPARTIC ACID; HYDROGENATION W. R. GRACE & CO. (US) 1987-12-01 US claimed
US-4668796-A Racemates of optically active bicyclic imino-alpha-carboxylic esters HOECHST AKTIENGESELLSCHAFT (DE) 1987-05-26 US claimed
US-20230410977-A1 METHODS AND MATERIALS FOR ASSESSING RADIATION EXPOSURE NUTECH VENTURES 2023-12-21 US disclosed
WO-2022140565-A1 METHODS AND MATERIALS FOR ASSESSING RADIATION EXPOSURE NUTECH VENTURES (US) 2022-06-30 WO disclosed
EP-3916003-A1 N-METHYL-D-ASPARTATE RECEPTOR MODULATORS AND METHODS OF MAKING AND USING SAME Naurex, Inc. (US) 2021-12-01 EP disclosed
EP-3171941-B1 N-METHYL-D-ASPARTATE RECEPTOR MODULATORS AND METHODS OF MAKING AND USING SAME NAUREX INC (US) 2021-03-24 EP disclosed
US-9994614-B2 N-methyl-D-aspartate receptor modulators and methods of making and using same NAUREX, INC. (US) 2018-06-12 US disclosed
US-20170210779-A1 N-METHYL-D-ASPARTATE RECEPTOR MODULATORS AND METHODS OF MAKING AND USING SAME NAUREX INC (US) 2017-07-27 US disclosed
EP-2353714-A1 ASYMMETRIC HYDROGENATION CATALYST Takasago International Corporation (JP) 2011-08-10 EP disclosed
US-7572607-B2 Polypeptides and biosynthetic pathways for the production of monatin and its precursors CARGILL, INCORPORATED (US) 2009-08-11 US disclosed
US-6277416-B1 CARRIER SYSTEM HAVING AT LEAST ONE WETTING AGENT AND HAVING AT LEAST ONE PENETRATION AGENT, WHEREIN SAID SOLUTION IS ABSORBED INTO THE DISEASED PLANT. CAMAS TECHNOLOGIES, INC. 2001-08-21 US disclosed
EP-0920336-A1 PESTICIDES COMPRISING BENZOPHENANTHRIDINE ALKALOIDS Camas Technologies, Inc. (US) 1999-06-09 EP disclosed
US-5789599-A Aziridine compounds, methods of preparation and reactions thereof DREXEL UNIVERSITY (US) 1998-08-04 US disclosed
WO-1997041890-A1 PESTICIDES COMPRISING BENZOPHENANTHRIDINE ALKALOIDS CAMAS TECHNOLOGIES, INC. (US) 1997-11-13 WO disclosed
US-5128478-A From aldehyde and isocyanato carboxylate AJINOMOTO CO., INC. (JP) 1992-07-07 US disclosed
US-4873359-A Process for preparing as partyl-phenylalanine dipeptides W. R. GRACE & CO. - CONN. (US) 1989-10-10 US disclosed
US-4810817-A ARTIFICIAL SWEETENERS W. R. GRACE & CO. (US) 1989-03-07 US disclosed
US-4710583-A ENZYMATIC COUPLING OF PHENYLSERINE WITH ASPARTIC ACID; HYDROGENATION W. R. GRACE & CO. (US) 1987-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170210779-A1 N-METHYL-D-ASPARTATE RECEPTOR MODULATORS AND METHODS OF MAKING AND USING SAME GRIN1, GRIN2A, GRIN3A LMNA 4777/4885NR1I2 537/4885PTGS1 613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.