SCHEMBL751652

SCHEMBL751652

N[C@H](C(=O)O)C(O)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.58
NR1I2 O75469 1/20 0.58
PTGS1 P23219 1/20 0.58
ADRA1A P35348 1/20 0.58
BLM P54132 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
ADRA2A P08913 1/20 0.56
ADRA2C P18825 1/20 0.56
HIF1A Q16665 1/20 0.56
KDM4E B2RXH2 1/20 0.56
MAPK1 P28482 1/20 0.54
ALDH1A1 P00352 1/20 0.54
ACHE P22303 1/20 0.51
DPP4 P27487 2/20 0.50
CYP2D6 P10635 1/20 0.50
SRC P12931 1/20 0.50
SLC1A3 P43003 1/20 0.47
SLC1A2 P43004 1/20 0.47
SLC1A1 P43005 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16816913 1.00 LMNA (0.58) LMNANR1I2PTGS1ADRA1ABLM
SCHEMBL17982719 1.00 LMNA (0.58) LMNANR1I2PTGS1ADRA1ABLM
SCHEMBL10535250 1.00 LMNA (0.58) LMNANR1I2PTGS1ADRA1ABLM
SCHEMBL8229978 1.00 LMNA (0.58) LMNANR1I2PTGS1ADRA1ABLM
SCHEMBL4728748 1.00 LMNA (0.58) LMNANR1I2PTGS1ADRA1ABLM
SCHEMBL4086543 1.00 LMNA (0.58) LMNANR1I2PTGS1ADRA1ABLM
SCHEMBL210030 1.00 LMNA (0.58) LMNANR1I2PTGS1ADRA1ABLM
SCHEMBL8528068 1.00 LMNA (0.58) LMNANR1I2PTGS1ADRA1ABLM
SCHEMBL443815 1.00 LMNA (0.58) LMNANR1I2PTGS1ADRA1ABLM
Hydrochloric Acid SCHEMBL6946154 0.98 ALDH1A1 (0.57) LMNANR1I2PTGS1ADRA1ABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1449 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4679087-A1 BIOMARKER AND USE THEREOF MEIJI CO., LTD (JP) 2026-01-14 EP claimed
US-20250296959-A1 B7-H3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF MARIANA ONCOLOGY INC (US) 2025-09-25 US claimed
WO-2024190663-A1 BIOMARKER AND USE THEREOF 株式会社明治 2024-09-19 WO claimed
CN-118561726-A Method for preparing 3-phenyl-L-serine or derivative thereof and ethyl ester thereof 苏州引航生物科技有限公司 2024-08-30 CN claimed
CN-118530962-A Modified threonine transaldolase and application thereof 苏州引航生物科技有限公司 2024-08-23 CN claimed
CN-114540335-B Immobilized modified threonine transaldolase and application thereof 湖南引航生物科技有限公司 2024-08-06 CN claimed
CN-113583989-B Modified threonine transaldolase and application thereof 苏州引航生物科技有限公司 2024-06-25 CN claimed
US-20240026396-A1 METHOD FOR PRODUCING TERTIARY BETA-HYDROXY-ALPHA-AMINO ACIDS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2024-01-25 US claimed
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2023-04-13 US claimed
CN-115819299-A Method for preparing 3-phenyl-L-serine or derivative and ethyl ester thereof 苏州引航生物科技有限公司 2023-03-21 CN claimed
EP-0115345-B1 PROCESS FOR THE RESOLUTION OF RACEMIC OPTICALLY ACTIVE BICYCLIC IMINO-ALPHA-CARBOXYLIC ACID ESTERS AND USE OF THE COMPOUNDS OBTAINABLE IN THIS WAY FOR THE SYNTHESIS OF CARBOXYALKYL DIPEPTIDES HOECHST AKTIENGESELLSCHAFT (DE) 1988-01-07 EP claimed
US-4710583-A ENZYMATIC COUPLING OF PHENYLSERINE WITH ASPARTIC ACID; HYDROGENATION W. R. GRACE & CO. (US) 1987-12-01 US claimed
EP-0226304-A1 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1987-06-24 EP claimed
EP-0220923-A2 Dipeptides and process W.R. Grace & Co.-Conn. (US) 1987-05-06 EP claimed
EP-0164389-B1 PREPARATION OF PHENYL ALANINES BY HYDROGENATION OF PHENYL SERINES ALKALOIDA VEGYéSZETI GYáR (HU) 1987-04-01 EP claimed
US-4605759-A ACIDIFYING THE REACTION PRODUCT OF GLYCINE, A BENZALDEHYDE AND GROUP 1 METAL HYDROXIDE USING WATER/SOLVENT MIXTURE AND A PHASE TRANSFER AGENT MITSUI TOATSU CHEMICALS, INC. (JP) 1986-08-12 US claimed
EP-0164389-A1 PREPARATION OF PHENYL ALANINES BY HYDROGENATION OF PHENYL SERINES. ALKALOIDA VEGYESZETI GYAR (HU) 1985-12-18 EP claimed
WO-1985002609-A1 PREPARATION OF PHENYL ALANINES BY HYDROGENATION OF PHENYL SERINES ALKALOIDA VEGYÉSZETI GYÁR (HU) 1985-06-20 WO claimed
US-4407952-A OF GENETICALLY ENGINEERED ESCHERICHIA AJINOMOTO COMPANY INCORPORATED (JP) 1983-10-04 US claimed
US-3930948-A ENZYMATIC METHOD FOR PRODUCING AROMATIC ETHYLAMINES AJINOMOTO CO., INC. (JA) 1976-01-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250296959-A1 B7-H3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF CD274, CD44, CD74 LMNA 3408/4885NR1I2 4578/4885PTGS1 4251/4885
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF TST, ABAT, AADAC LMNA 4387/4885NR1I2 4392/4885PTGS1 4428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.