SCHEMBL4086671

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4093637	0.91	MAOB (0.48)	DHFRMAOBHSP90AA1HSP90AB1LRRK2
	SCHEMBL14642116	0.88	DHFR (0.42)	DHFRHSP90AA1HSP90AB1LRRK2TYMS
	SCHEMBL4086287	0.86	DHFR (0.40)	DHFRHSP90AA1HSP90AB1LRRK2TYMS
	SCHEMBL4094840	0.85	DHFR (0.39)	DHFRHSP90AA1HSP90AB1LRRK2TYMS
	SCHEMBL4095647	0.84	MEN1 (0.39)	DHFRLRRK2TYMSEGFRKDR
	SCHEMBL4102784	0.83	HSP90AB1 (0.45)	DHFRMAOBHSP90AA1HSP90AB1LRRK2
	SCHEMBL4093475	0.82	NPC1 (0.43)	DHFRHSP90AA1HSP90AB1LRRK2TYMS
	SCHEMBL4093485	0.82	DHFR (0.46)	DHFRHSP90AA1HSP90AB1LRRK2TYMS
	SCHEMBL4093607	0.78	DHFR (0.42)	DHFRHSP90AA1HSP90AB1LRRK2TYMS
	SCHEMBL15101660	0.77	TSHR (0.42)	ADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.