SCHEMBL4095647

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15101660	0.93	TSHR (0.42)	MEN1KMT2AACACATSHRPOLB
	SCHEMBL14642116	0.88	DHFR (0.42)	DHFRTYMSEGFRKDRLRRK2
	SCHEMBL4086287	0.87	DHFR (0.40)	DHFRTSHRTYMSEGFRKDR
	SCHEMBL4094840	0.86	DHFR (0.39)	DHFRTYMSEGFRKDRLRRK2
	SCHEMBL4093637	0.85	MAOB (0.48)	DHFRTYMSEGFRKDRLRRK2
	SCHEMBL4086671	0.84	DHFR (0.39)	DHFRTYMSEGFRKDRLRRK2
	SCHEMBL4093475	0.83	NPC1 (0.43)	DHFRTYMSEGFRKDRLRRK2
	SCHEMBL4093485	0.81	DHFR (0.46)	DHFRTYMSEGFRKDRLRRK2
	SCHEMBL4093607	0.77	DHFR (0.42)	KMT2ADHFRTSHRMAPTTYMS
	SCHEMBL4094689	0.76	LRRK2 (0.43)	DHFRTYMSEGFRKDRLRRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.