Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KLK7 | P49862 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4086777 | 0.81 | MAPT (0.58) | HTTRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL699996 | 0.81 | MAPT (0.58) | HTTRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL31185236 | 0.81 | HTT (0.68) | HTTRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL147291 | 0.81 | HTT (0.73) | HTTRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL29279417 | 0.81 | HTT (0.68) | HTTRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL8255335 | 0.79 | RAB9A (0.61) | HTTRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL18137202 | 0.79 | KMT2A (0.54) | HTTRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL701232 | 0.79 | KMT2A (0.54) | HTTRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL2608943 | 0.79 | HTT (0.70) | HTTRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL16788260 | 0.78 | KMT2A (0.55) | HTTRAB9ANPC1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423211-B1 | PROCESSES FOR PRODUCING (1S,6S)- OR (1R,6R)-CIS-2,8-DIAZABICYCLO[4.3.0]NONANE AND INTERMEDIATE THEREOF | KANEKA CORP (JP) | 2014-04-16 | — | — | EP | disclosed |
| EP-2423211-A1 | PROCESSES FOR PRODUCING (1S,6S)- OR (1R,6R)-CIS-2,8-DIAZABICYCLO[4.3.0]NONANE AND INTERMEDIATE THEREOF | Kaneka Corporation (JP) | 2012-02-29 | — | — | EP | disclosed |