Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29900980 | 0.88 | LMNA (0.51) | LMNAL3MBTL1TSHRADRA2CALDH1A1 | |
| SCHEMBL30613500 | 0.83 | ADRA2C (0.58) | LMNAL3MBTL1ADRA2CALDH1A1POLB | |
| SCHEMBL5415267 | 0.78 | KCNH2 (0.50) | LMNAL3MBTL1TSHRALDH1A1POLB | |
| SCHEMBL14610381 | 0.78 | KCNH2 (0.49) | LMNAL3MBTL1TSHRALDH1A1POLB | |
| SCHEMBL13310580 | 0.78 | LMNA (0.43) | LMNAL3MBTL1ADRA2CALDH1A1POLB | |
| SCHEMBL29994960 | 0.78 | POLB (0.56) | LMNAL3MBTL1TSHRALDH1A1POLB | |
| SCHEMBL15929449 | 0.78 | ALDH1A1 (0.51) | LMNATSHRALDH1A1KMT2AKCNH2 | |
| SCHEMBL4651250 | 0.78 | LMNA (0.47) | LMNAL3MBTL1ADRA2CALDH1A1POLB | |
| SCHEMBL12653659 | 0.77 | LMNA (0.45) | LMNAL3MBTL1ADRA2CALDH1A1POLB | |
| SCHEMBL1839002 | 0.76 | LMNA (0.52) | LMNAL3MBTL1ALDH1A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049028-A1 | PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USE AS JANUS KINASE MODULATORS | TARGEGEN INC. (US) | 2009-04-16 | — | — | WO | disclosed |