Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22698176 | 0.96 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL19884699 | 0.96 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL23378084 | 0.94 | TSHR (0.65) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL164047 | 0.88 | THRB (0.57) | TSHRTHRBPOLBAPEX1HTT | |
| Ammonia Solution, Strong SCHEMBL28190576 | 0.86 | THRB (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28189930 | 0.86 | THRB (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL182045 | 0.85 | TSHR (0.72) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL278570 | 0.85 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9162964 | 0.83 | TSHR (0.69) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11600594 | 0.83 | TSHR (0.69) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120115108-A1 | POLYMERIZABLE PHOSPHORIC ACID DERIVATIVES COMPRISING A POLYALICYLIC STRUCTURE ELEMENT | VOCO GMBH (DE) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115108-A1 | POLYMERIZABLE PHOSPHORIC ACID DERIVATIVES COMPRISING A POLYALICYLIC STRUCTURE ELEMENT | CAD, PCBP1, PPIP5K2 | TSHR 4604/4885THRB 3418/4885POLB 591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.