SCHEMBL4087391

SCHEMBL4087391

C=C(C)C(=O)OCCNC(=O)OCC

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.55
TSHR P16473 3/20 0.49
L3MBTL1 Q9Y468 1/20 0.47
ACHE P22303 8/20 0.43
GLA P06280 1/20 0.40
KMT2A Q03164 1/20 0.40
ALDH1A1 P00352 1/20 0.39
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13309598 0.92 THRB (0.64) THRBTSHRL3MBTL1ACHEGLA
SCHEMBL8928140 0.90 TSHR (0.54) THRBTSHRACHE
SCHEMBL6255228 0.89 THRB (0.45) THRBTSHRL3MBTL1ACHEALDH1A1
SCHEMBL2403793 0.89 THRB (0.53) THRBTSHRL3MBTL1ACHEALDH1A1
SCHEMBL13872030 0.89 THRB (0.53) THRBTSHRL3MBTL1ACHEALDH1A1
SCHEMBL15128211 0.89 THRB (0.47) THRBTSHRL3MBTL1ACHEMGAM
SCHEMBL17225745 0.88 TSHR (0.57) THRBTSHRACHE
SCHEMBL6253394 0.88 TSHR (0.51) THRBTSHRACHE
SCHEMBL6256032 0.87 THRB (0.72) THRBTSHRL3MBTL1ACHEALDH1A1
SCHEMBL10331942 0.87 ACHE (0.54) THRBTSHRACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005055959-A2 BULKY MONOMERS LEADING TO RESINS EXHIBITING LOW POLYMERIZATION SHRINKAGE E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-06-23 WO claimed
US-20050124721-A1 Bulky monomers leading to resins exhibiting low polymerization shrinkage E. I. DU PONT DE NEMOURS AND COMPANY 2005-06-09 US claimed
EP-4581069-A1 ANAEROBICALLY CURABLE COMPOSITIONS Henkel AG & Co. KGaA (DE) 2025-07-09 EP disclosed
US-20250197690-A1 ANAEROBICALLY CURABLE COMPOSITIONS HENKEL AG & CO KGAA (DE) 2025-06-19 US disclosed
US-12044968-B2 Protective film-forming composition having acetal structure and amide structure NISSAN CHEMICAL CORPORATION (JP) 2024-07-23 US disclosed
US-12044968-B2 Protective film-forming composition having acetal structure and amide structure NISSAN CHEMICAL CORPORATION (JP) 2024-07-23 US disclosed
US-12037463-B2 Antimicrobial ophthalmic devices comprising polysiloxane-polyglycerol block copolymers and methods of making and use thereof Clearlab Sg Pte Ltd. (SG) 2024-07-16 US disclosed
WO-2024046703-A1 ANAEROBICALLY CURABLE COMPOSITIONS HENKEL AG & CO. KGAA (DE) 2024-03-07 WO disclosed
US-20240066790-A1 Process and apparatus for locally polymerizing a starting material by dual color photopolymerization and method for volumetric printing of a shaped body XOLO GMBH (DE) 2024-02-29 US disclosed
EP-4326789-A1 ANAEROBICALLY CURABLE COMPOSITIONS Henkel AG & Co. KGaA (DE) 2024-02-28 EP disclosed
US-20240052219-A1 ANAEROBICALLY CURABLE COMPOSITIONS HENKEL AG & CO KGAA (DE) 2024-02-15 US disclosed
WO-2005055959-A2 BULKY MONOMERS LEADING TO RESINS EXHIBITING LOW POLYMERIZATION SHRINKAGE E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-06-23 WO disclosed
WO-2005055961-A1 DENTAL COMPOSITIONS CONTAINING CORE-SHELL POLYMERS WITH LOW MODULUS CORES E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-06-23 WO disclosed
US-20050124721-A1 Bulky monomers leading to resins exhibiting low polymerization shrinkage E. I. DU PONT DE NEMOURS AND COMPANY 2005-06-09 US disclosed
US-20050124762-A1 Dental compositions containing core-shell polymers with low modulus cores E. I. DU PONT DE NEMOURS AND COMPANY 2005-06-09 US disclosed
US-5840806-A COMPOSITION COMPRISING RESIN FORMED BY CONDENSATION OF POLYSILOXANE WITH POLYMER HAVING HYDROLYZABLE SILYL GROUP AND ADDITIONAL FUNCTIONAL GROUP, COMPOUND CAPABLE OF REACTING WITH SAID GROUP DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-11-24 US disclosed
EP-0495269-B1 Thermosetting reactive resin mixture, moulded article and coating made therefrom DAINIPPON INK & CHEMICALS (JP) 1997-03-05 EP disclosed
US-5292833-A Polyepoxide compound, carbamate compound and catalyst DAINIPPON INK AND CHEMICALS, INC. (JP) 1994-03-08 US disclosed
WO-1992012192-A2 THERMOSETTING REACTIVE RESIN MIXTURE, MOULDED ARTICLE AND COATING MADE THEREFROM DAINIPPON INK & CHEMICALS, INC. (JP) 1992-07-23 WO disclosed
EP-0495269-A2 Thermosetting reactive resin mixture, moulded article and coating made therefrom DAINIPPON INK AND CHEMICALS, INC. (JP) 1992-07-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050124721-A1 Bulky monomers leading to resins exhibiting low polymerization shrinkage REV1, TERB1, RAD51 THRB 4766/4885TSHR 4811/4885L3MBTL1 2857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.