SCHEMBL408749

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL406824	0.81	KDM4E (0.41)	ACHEGRIN1GRIN2AGRIN2DGRIN3B
	SCHEMBL408088	0.79	BAZ2B (0.52)	MAP2BAZ2BGAA
	SCHEMBL407032	0.79	ACHE (0.46)	ACHEGRIN1GRIN2AGRIN2DGRIN3B
	SCHEMBL10139987	0.78	ACHE (0.40)	ACHEGRIN1GRIN2AGRIN2DGRIN3B
	SCHEMBL406674	0.78	KDM4E (0.43)	ACHEGRIN1GRIN2AGRIN2DGRIN3B
	Hydrochloric Acid SCHEMBL409118	0.77	ACHE (0.39)	ACHEGRIN1GRIN2AGRIN2DGRIN3B
	SCHEMBL12480316	0.76	CHRNA7 (0.50)	BAZ2BPOLBGAA
	SCHEMBL10139825	0.72	BAZ2B (0.53)	BAZ2BGAA
	SCHEMBL24101581	0.72	KDM4E (0.38)	BAZ2B
	SCHEMBL30340105	0.72	KDM4E (0.38)	BAZ2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.