SCHEMBL4087556

SCHEMBL4087556

C=CCN([C]=O)C(=O)C=C

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7523082 0.80 ZDHHC20 (0.35) ALDH1A1LMNA
SCHEMBL4933350 0.79
SCHEMBL6922595 0.77 ALDH1A1 (0.45) ALDH1A1
SCHEMBL4440625 0.77
SCHEMBL27949 0.76 ALDH1A1 (0.39) ALDH1A1
SCHEMBL4952774 0.75 SMN1; SMN2 (0.39) ALDH1A1LMNA
SCHEMBL49389 0.70 ALDH1A1 (0.52) ALDH1A1LMNA
SCHEMBL676588 0.69
SCHEMBL6445195 0.67 ALDH1A1 (0.38) ALDH1A1LMNA
SCHEMBL433690 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7497970-B2 Chiral agent for liquid crystal, liquid crystal composition and polymer, as well as filter for optical recording medium, optical recording medium and color filter liquid for crystal FUJIFILM CORPORATION (JP) 2009-03-03 US disclosed
US-20070228325-A1 Chiral agent for liquid crystal, liquid crystal composition and polymer, as well as filter for optical recording medium, optical recording medium and color filter liquid for crystal FUJIFILM CORPORATION (JP) 2007-10-04 US disclosed
US-6156781-A Substituted pyrazolyl benzenesulfonamides for the treatment of inflammation G. D. SEARLE & CO. (US) 2000-12-05 US disclosed