SCHEMBL4087612

SCHEMBL4087612

CCNC(=S)n1c(-c2cc(OC)c(O)c(OC)c2)nc(-c2ccc(N(CC)CC)cc2)c1-c1ccc(N(CC)CC)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMPD3 Q9NY59 5/20 0.37
MAPT P10636 5/20 0.34
ALDH1A1 P00352 4/20 0.34
NPSR1 Q6W5P4 3/20 0.34
TP53 P04637 2/20 0.34
HPGD P15428 2/20 0.34
GAA P10253 2/20 0.34
HTT P42858 2/20 0.34
MAPK1 P28482 2/20 0.34
KDM4E B2RXH2 1/20 0.34
USP2 O75604 1/20 0.34
LMNA P02545 1/20 0.34
ESR1 P03372 1/20 0.34
GLA P06280 1/20 0.34
TSHR P16473 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HSD17B10 Q99714 1/20 0.34
NOX1 Q9Y5S8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9684907 0.92 SMPD3 (0.35) SMPD3MAPTTP53NOX1
SCHEMBL9099285 0.85 SMPD3 (0.40) SMPD3MAPTALDH1A1NPSR1TP53
SCHEMBL10914827 0.83 SMPD3 (0.38) SMPD3MAPTALDH1A1NPSR1TP53
SCHEMBL9683714 0.82 SMPD3 (0.36) SMPD3MAPTTP53NOX1
SCHEMBL9494004 0.81 SMPD3 (0.40) SMPD3MAPTALDH1A1NPSR1TP53
SCHEMBL12152129 0.81 TEK (0.40) SMPD3MAPTALDH1A1NPSR1TP53
SCHEMBL9684929 0.80 ALDH1A1 (0.36) SMPD3MAPTALDH1A1NPSR1HPGD
SCHEMBL10082739 0.78 FABP4 (0.36) SMPD3MAPTALDH1A1NPSR1GAA
SCHEMBL9683860 0.78 KDM1A (0.38) MAPTALDH1A1NPSR1HPGDGAA
SCHEMBL9683799 0.77 SMPD3 (0.37) SMPD3MAPTALDH1A1NPSR1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118382704-A Method for reducing measurement error caused by haemoglobin 东洋纺株式会社 2024-07-23 CN disclosed
WO-2023190087-A1 ENHACEMENT OF ACCURACY WHEN MEASURING HIGH-CREATININE-VALUE SPECIMEN 東洋紡株式会社 2023-10-05 WO disclosed
WO-2023085323-A1 METHOD FOR REDUCING MEASUREMENT ERRORS DUE TO HEMOLYZED HEMOGLOBIN 東洋紡株式会社 2023-05-19 WO disclosed
EP-1271143-B1 Test strip having a porous filter layer ARKRAY INC (JP) 2009-05-06 EP disclosed
US-7201871-B2 Specimen having capability of separating solid component ARKRAY INC. (JP) 2007-04-10 US disclosed
US-7189576-B2 Method for measuring substance and testing piece ARKRAY INC. (JP) 2007-03-13 US disclosed
US-7153696-B2 Method for measuring substance and testing piece ARKRAY INC. (JP) 2006-12-26 US disclosed
US-7098038-B2 Method for measuring substance and testing piece ARKRAY INC. (JP) 2006-08-29 US disclosed
EP-0860695-B1 Method for measuring an analyte and corresponding device ARKRAY INC (JP) 2006-01-04 EP disclosed
US-6777243-B2 MEASURING DETECTABLE SUBSTANCE BY USING AQUEOUS REACTION SYSTEM INCLUDING FORMATION REACTION OF DETECTABLE SUBSTANCE BASED ON CHEMICAL REACTION OF ANALYTE CONTAINED IN SAMPLE; REACTING IN PRESENCE OF LAYERED INORGANIC COMPOUND ARKRAY INC. (JP) 2004-08-17 US disclosed
US-20030180183-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-25 US disclosed
US-20030175985-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-18 US disclosed
US-20030175984-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-18 US disclosed
US-20030166295-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-04 US disclosed
US-20030044316-A1 Specimen having capability of separating solid component ARKRAY INC. (JP) 2003-03-06 US disclosed
EP-1271143-A1 SPECIMEN HAVING CAPABILITY OF SEPARATING SOLID COMPONENT ARKRAY, Inc. (JP) 2003-01-02 EP disclosed
EP-0860695-A9 METHOD OF MEASUREMENT OF MATERIAL AND TESTPIECE KABUSHIKI KAISHA KYOTO DAIICHI KAGAKU (JP) 2001-10-17 EP disclosed
EP-0860695-A1 METHOD OF MEASUREMENT OF MATERIAL AND TESTPIECE KABUSHIKI KAISHA KYOTO DAIICHI KAGAKU (JP) 1998-08-26 EP disclosed
US-5164512-A Triarylimidazole derivative, determination of hydrogen peroxide generated by enzymatic reaction WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1992-11-17 US disclosed
EP-0404526-A1 Oxidizable color producing reagent WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1990-12-27 EP disclosed