Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TEK | Q02763 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12152129 | 0.88 | TEK (0.40) | SMPD3ALDH1A1KDM4ELMNATP53 | |
| SCHEMBL14445889 | 0.87 | TUBB4A (0.43) | SMPD3ALDH1A1KDM4ELMNATP53 | |
| SCHEMBL9099285 | 0.86 | SMPD3 (0.40) | SMPD3ALDH1A1KDM4ELMNATP53 | |
| SCHEMBL14445896 | 0.83 | SMPD3 (0.53) | SMPD3TEKNOX1FGFR1 | |
| SCHEMBL10914827 | 0.82 | SMPD3 (0.38) | SMPD3ALDH1A1KDM4ELMNATP53 | |
| SCHEMBL4087612 | 0.81 | SMPD3 (0.37) | SMPD3ALDH1A1KDM4ELMNATP53 | |
| SCHEMBL14446518 | 0.81 | FABP4 (0.44) | ALDH1A1KDM4ELMNATP53MAPT | |
| SCHEMBL10082739 | 0.81 | FABP4 (0.36) | SMPD3ALDH1A1LMNAMAPTGAA | |
| SCHEMBL9684929 | 0.79 | ALDH1A1 (0.36) | SMPD3ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL14446724 | 0.79 | KDM4E (0.38) | ALDH1A1KDM4ELMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272578-B1 | MULTILAYER ANALYSIS ELEMENTS FOR THE DETERMINATION OF TOTAL CHOLESTEROL | Fuji Photo Film Co., Ltd. (JP) | 1993-03-24 | — | — | EP | disclosed |
| EP-0244825-A1 | Dry-type analytical element for cholesterol | FUJI PHOTO FILM CO., LTD. (JP) | 1987-11-11 | — | — | EP | disclosed |