Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PDE8B | O95263 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FPR3 | P25089 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30344858 | 0.90 | HSD17B10 (0.40) | HSD17B10SMN1; SMN2ALDH1A1ATM | |
| SCHEMBL133363 | 0.87 | L3MBTL1 (0.58) | HSD17B10SMN1; SMN2OPRD1ALDH1A1L3MBTL1 | |
| SCHEMBL47049 | 0.87 | L3MBTL1 (0.58) | HSD17B10SMN1; SMN2OPRD1ALDH1A1L3MBTL1 | |
| SCHEMBL135177 | 0.87 | L3MBTL1 (0.58) | HSD17B10SMN1; SMN2OPRD1ALDH1A1L3MBTL1 | |
| SCHEMBL4093876 | 0.85 | HSD17B10 (0.48) | HSD17B10SMN1; SMN2OPRD1ALDH1A1L3MBTL1 | |
| SCHEMBL639097 | 0.84 | ATM (0.49) | HSD17B10SMN1; SMN2OPRD1ALDH1A1L3MBTL1 | |
| SCHEMBL3420227 | 0.84 | ATM (0.49) | HSD17B10SMN1; SMN2OPRD1ALDH1A1L3MBTL1 | |
| SCHEMBL115698 | 0.84 | ATM (0.49) | HSD17B10SMN1; SMN2OPRD1ALDH1A1L3MBTL1 | |
| SCHEMBL3576321 | 0.84 | HSD17B10 (0.49) | HSD17B10SMN1; SMN2OPRD1ALDH1A1L3MBTL1 | |
| SCHEMBL1467517 | 0.84 | HSD17B10 (0.49) | HSD17B10SMN1; SMN2OPRD1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203763-A1 | SUBSTITUTED BENZHYDRYLETHERS | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-08-13 | — | — | US | disclosed |
| US-20090203763-A1 | SUBSTITUTED BENZHYDRYLETHERS | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203763-A1 | SUBSTITUTED BENZHYDRYLETHERS | UGT2B7, CYP3A7, CYP3A43 | HSD17B10 159/4885SMN1; SMN2 1769/4885OPRD1 1551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.