Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 6/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4380885 | 0.97 | FAAH (0.45) | FAAHALOX5APALOX5PLA2G2APTGS2 | |
| SCHEMBL4088424 | 0.93 | FAAH (0.47) | FAAHALOX5APALOX5PLA2G2APTGS1 | |
| SCHEMBL4083416 | 0.91 | F2RL3 (0.35) | FAAHALOX5APALOX5PLA2G2AMAPT | |
| SCHEMBL4088689 | 0.90 | FAAH (0.44) | FAAHALOX5APALOX5PTGS1PTGS2 | |
| SCHEMBL2993129 | 0.90 | FAAH (0.51) | FAAHALOX5APALOX5PLA2G2AMAPT | |
| SCHEMBL2995166 | 0.89 | FAAH (0.46) | FAAHALOX5APALOX5PLA2G2APTGS1 | |
| SCHEMBL4101976 | 0.89 | FAAH (0.53) | FAAHALOX5APALOX5PTGS1MAPT | |
| SCHEMBL4562856 | 0.89 | FAAH (0.53) | FAAHALOX5APALOX5PTGS1MAPT | |
| SCHEMBL4090379 | 0.88 | FAAH (0.42) | FAAHALOX5APALOX5MAPT | |
| SCHEMBL4088383 | 0.87 | FAAH (0.46) | FAAHALOX5APALOX5CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2610244-A1 | Indole compounds | Ironwood Pharmaceuticals, Inc. (US) | 2013-07-03 | — | — | EP | disclosed |
| US-20090118503-A1 | FAAH INHIBITORS | IRONWOOD PHARMACEUTICALS, INC. | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118503-A1 | FAAH INHIBITORS | FAAH, FAAH2, CNR2 | FAAH 1/4885ALOX5AP 26/4885ALOX5 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.