Acetylcholine

Acetylcholine

SCHEMBL40885

CC(=O)OCC[N+](C)(C)C.[Cl-]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CHRM3

The experimentally established mechanism targets of Acetylcholine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM3 known ✓ P20309 6/20 1.00
CHRM5 P08912 6/20 1.00
CHRM1 P11229 6/20 1.00
CHRM2 P08172 5/20 0.95
CHRM4 P08173 5/20 0.95
CHRNB2 P17787 4/20 0.95
CHRNA4 P43681 4/20 0.95
CHRNA7 P36544 3/20 0.95
HTR1A P08908 2/20 0.95
SMN1; SMN2 Q16637 2/20 0.95
PGR P06401 1/20 0.95
TBXA2R P21731 1/20 0.95
CHRNB4 P30926 1/20 0.95
CHRNA3 P32297 1/20 0.95
CHRNA10 Q9GZZ6 1/20 0.95
CHRNA9 Q9UGM1 1/20 0.95
GALR3 O60755 2/20 0.91
GAA P10253 1/20 0.91
RAB9A P51151 1/20 0.91
MAPT P10636 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetylcholine SCHEMBL27920125 1.00 CHRM5 (1.00) CHRM5CHRM1CHRM3CHRM2CHRM4
Acetylcholine SCHEMBL27479902 0.98 CHRM5 (0.95) CHRM5CHRM1CHRM3CHRM2CHRM4
Acetylcholine SCHEMBL5468500 0.98 CHRM5 (0.95) CHRM5CHRM1CHRM3CHRM2CHRM4
Acetylcholine SCHEMBL31072232 0.98 CHRM5 (0.95) CHRM5CHRM1CHRM3CHRM2CHRM4
Acetylcholine SCHEMBL3753925 0.98 CHRM5 (0.95) CHRM5CHRM1CHRM3CHRM2CHRM4
Acetylcholine SCHEMBL27591882 0.98 CHRM5 (0.95) CHRM5CHRM1CHRM3CHRM2CHRM4
Acetylcholine SCHEMBL2518957 0.97 CHRM1 (1.00) CHRM5CHRM1CHRM3CHRM2CHRM4
Acetylcholine SCHEMBL3216 0.97 CHRM1 (1.00) CHRM5CHRM1CHRM3CHRM2CHRM4
Acetylcholine SCHEMBL1899186 0.95 CHRM1 (0.95) CHRM5CHRM1CHRM3CHRM2CHRM4
Acetylcholine SCHEMBL8513991 0.95 CHRM1 (0.95) CHRM5CHRM1CHRM3CHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4195 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118406492-B Preparation method and application of metal doped carbon dots 北京师范大学 2026-05-15 CN claimed
US-20260076872-A1 POLYMER VIALS WITH SUBSTANTIALLY FLAT BOTTOMS AND INJECTION STRETCH BLOW MOLDING METHODS FOR MAKING THE SAME SIO2 MEDICAL PRODUCTS LLC (US) 2026-03-19 US claimed
US-20250242092-A1 SiOx BARRIER FOR PHARMACEUTICAL PACKAGE AND COATING PROCESS SIO2 MEDICAL PRODUCTS INC (US) 2025-07-31 US claimed
CN-120064485-A LC-MS/MS-based method for determining one-carbon metabolic pathway substances in plasma sample 武汉迈维代谢生物科技股份有限公司 2025-05-30 CN claimed
US-20250136841-A1 BLENDED FURNISH WITH IMPROVED PERFORMANCE AND METHODS OF MAKING AND USING THE SAME ARCLIN USA LLC (US) 2025-05-01 US claimed
CN-119798690-A MOF material, preparation method and application thereof, and CO2Adsorbent and process for producing the same 清华大学 2025-04-11 CN claimed
CN-119798205-A CO2Method for preparing cyclic carbonate by cycloaddition with epoxide and application thereof 清华大学 2025-04-11 CN claimed
CN-115868584-B Artificial feed for larva of pteroceltis and preparation method and application thereof 南京林业大学 2025-03-25 CN claimed
US-12257371-B2 SiOx barrier for pharmaceutical package and coating process SIO2 MEDICAL PRODUCTS, LLC (US) 2025-03-25 US claimed
CN-119591817-A Fluorescent composite material, using method and sensor using fluorescent composite material 重庆大学 2025-03-11 CN claimed
WO-1997006782-A1 COMPOSITIONS INCLUDING O-CARBOXYALKYL CHITOSAN AND METHODS OF USE IN OPHTHALMICS NOVARTIS AG (CH) 1997-02-27 WO claimed
WO-1997000669-A1 COMPOSITIONS AND METHODS FOR STABILIZING POLYMERS NOVARTIS AG (CH) 1997-01-09 WO claimed
WO-1996032951-A1 CONTROLLED RELEASE OF MIOTIC AND MYDRIATIC DRUGS IN THE ANTERIOR CHAMBER GALIN MILES A (US) 1996-10-24 WO claimed
EP-0291177-B1 NOVEL COMPOSITIONS FOR PERCUTANEOUS EMBOLIZATION Biomatrix, Inc. (US) 1992-04-01 EP claimed
CN-1007839-B Compositions of liquid ion exchangers for use as acetylcholinergic ion-selective microelectrodes UNIV ZHEJIANG (CN) 1990-05-02 CN claimed
CN-1030480-A The preparation technology of liquid ion-exchanger composite used as acetylcholine ion-selective microelectrode UNIV ZHEJIANG (CN) 1989-01-18 CN claimed
US-4795741-A Compositions for therapeutic percutaneous embolization and the use thereof BIOMATRIX, INC. (US) 1989-01-03 US claimed
EP-0291177-A2 Novel compositions for percutaneous embolization Biomatrix, Inc. (US) 1988-11-17 EP claimed
EP-0152379-A2 Process for preparing pharmaceutical compositions containing unilamellar liposomes CIBA-GEIGY AG (CH) 1985-08-21 EP claimed
US-4245050-A FROM BREVIBACTERIA OR CORYNEBACTERIA KYOWA HAKKO KOGYO CO., LTD. (JP) 1981-01-13 US claimed