Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acetylcholine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 known ✓ | P20309 | 8/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 8/20 | 1.00 |
| ▸ | CHRM2 | P08172 | 7/20 | 1.00 |
| ▸ | CHRM4 | P08173 | 7/20 | 1.00 |
| ▸ | CHRM5 | P08912 | 6/20 | 1.00 |
| ▸ | CHRNB2 | P17787 | 4/20 | 1.00 |
| ▸ | CHRNA4 | P43681 | 4/20 | 1.00 |
| ▸ | CHRNA7 | P36544 | 3/20 | 1.00 |
| ▸ | HTR1A | P08908 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | PGR | P06401 | 1/20 | 1.00 |
| ▸ | TBXA2R | P21731 | 1/20 | 1.00 |
| ▸ | CHRNB4 | P30926 | 1/20 | 1.00 |
| ▸ | CHRNA3 | P32297 | 1/20 | 1.00 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 1.00 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 1.00 |
| ▸ | GALR3 | O60755 | 2/20 | 0.95 |
| ▸ | GAA | P10253 | 1/20 | 0.95 |
| ▸ | RAB9A | P51151 | 1/20 | 0.95 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetylcholine SCHEMBL3216 | 1.00 | CHRM1 (1.00) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| Acetylcholine SCHEMBL15687718 | 0.97 | CHRM1 (0.95) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| Acetylcholine SCHEMBL21925712 | 0.97 | CHRM1 (0.95) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| Acetylcholine SCHEMBL1157050 | 0.97 | CHRM1 (0.95) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| Acetylcholine SCHEMBL6023859 | 0.97 | CHRM1 (0.95) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| Acetylcholine SCHEMBL1899186 | 0.97 | CHRM1 (0.95) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| Acetylcholine SCHEMBL18227923 | 0.97 | CHRM1 (0.95) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| Acetylcholine SCHEMBL8513991 | 0.97 | CHRM1 (0.95) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| Acetylcholine SCHEMBL3904052 | 0.97 | CHRM1 (0.95) | CHRM1CHRM3CHRM2CHRM4CHRM5 | |
| Acetylcholine SCHEMBL40885 | 0.97 | CHRM5 (1.00) | CHRM1CHRM3CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110247494-A1 | LIQUID SORBANT, METHOD OF USING A LIQUID SORBANT, AND DEVICE FOR SORBING A GAS | VTU Holding GmbH. (AT) | 2011-10-13 | — | — | US | claimed |
| WO-2024003412-A1 | METHODS FOR DETERMINING IMPAIRMENTS IN NEURO-METABOLISM IN A SUBJECT IN NEED THEREOF & MEANS USEFUL IN THE TREATMENT THEREOF | HEALTHY-LONGER GMBH (CH) | 2024-01-04 | — | — | WO | disclosed |
| CN-113871528-A | Neuron receptor mediated artificial synapse device and preparation method thereof | 南开大学 | 2021-12-31 | — | — | CN | disclosed |
| CN-213285332-U | Novel medical treatment formula multifrequency increases looks appearance | 湖南亚纳秒健康产业有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-212935869-U | Alternating current pulse current generation modulation circuit | 湖南亚纳秒健康产业有限公司 | 2021-04-09 | — | — | CN | disclosed |
| CN-110506906-A | A kind of infant rice powder and its preparation process containing benthophyte | SHANTOU MEIHENG TETRA BIOTECHNOLOGY CO LTD | 2019-11-29 | — | — | CN | disclosed |
| CN-110403945-A | Composite vitamin composition for promoting gastrointestinal system power and preparation method thereof | ZENSUN SHANGHAI SCIENCE & TECH LIMITED | 2019-11-05 | — | — | CN | disclosed |
| CN-110022882-A | Promote the compound vitamin composition of gastronintestinal system power | 上海泽生科技开发股份有限公司 | 2019-07-16 | — | — | CN | disclosed |
| CN-108651996-A | A kind of brain tonic and intelligence development alimentation composition and its application | 广东康侨药业有限公司 | 2018-10-16 | — | — | CN | disclosed |
| CN-108289849-A | Compound preparation of mosapride and rabeprazole | 韩国联合制药株式会社 | 2018-07-17 | — | — | CN | disclosed |
| CN-105209066-A | Mono or multivalent botulinum neurotoxin based vaccine using the heavy chain from serotypes of clostridium botulinum | UNIV PENNSYLVANIA | 2015-12-30 | — | — | CN | disclosed |
| CN-204924926-U | Gamma - glutamy transpeptidase detect reagent box | SHANGHAI ZHICHENG BIOLOG TECHNOLOGY CO LTD | 2015-12-30 | — | — | CN | disclosed |
| CN-102764279-B | Method and composition for modifying cyte functions | ALLTECH INC | 2015-04-01 | — | — | CN | disclosed |
| CN-104306405-A | Health suppository with capabilities of improving anorectal immunity and preventing constipation and anorectal disease as well as preparation method and application of health suppository | ZHU DONGFENG | 2015-01-28 | — | — | CN | disclosed |
| CN-103877107-A | Application of notoginsenoside R1 | UNIV BEIJING NORMAL | 2014-06-25 | — | — | CN | disclosed |
| CN-102448328-A | Nutritional composition for supporting brain development and function in infants | NESTEC SA | 2012-05-09 | — | — | CN | disclosed |
| US-20110247494-A1 | LIQUID SORBANT, METHOD OF USING A LIQUID SORBANT, AND DEVICE FOR SORBING A GAS | VTU Holding GmbH. (AT) | 2011-10-13 | — | — | US | disclosed |
| CN-101606728-A | Has fish head food of health care and preparation method thereof | CHONGGUO JIANG (CN) | 2009-12-23 | — | — | CN | disclosed |
| CN-1802155-A | Nerve cell protective agent | EISAI CO LTD (JP) | 2006-07-12 | — | — | CN | disclosed |
| CN-1352958-A | Chinese Medicine for treating disease and improving intelligence | QI JIAHE (CN) | 2002-06-12 | — | — | CN | disclosed |