Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL440254 | 0.87 | EPHX2 (0.30) | EPHX2 | |
| SCHEMBL440256 | 0.87 | EPHX2 (0.30) | EPHX2 | |
| SCHEMBL440255 | 0.87 | EPHX2 (0.30) | EPHX2 | |
| SCHEMBL440897 | 0.86 | BRD4 (0.34) | EPHX2 | |
| SCHEMBL440898 | 0.86 | BRD4 (0.34) | EPHX2 | |
| SCHEMBL408866 | 0.86 | BRD4 (0.34) | EPHX2 | |
| SCHEMBL408780 | 0.77 | ENPP2 (0.35) | MAPTEPHX2 | |
| SCHEMBL407984 | 0.77 | ENPP2 (0.35) | MAPTEPHX2 | |
| SCHEMBL439064 | 0.74 | DPP4 (0.33) | EPHX2 | |
| SCHEMBL407401 | 0.72 | EPHX2 (0.34) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | DGAT2, DGAT1, DLAT | NOTUM 255/4885MAPT 1464/4885EPHX2 1660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.