Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 5/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CETP | P11597 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4083428 | 0.94 | HDAC1 (0.60) | HDAC3HDAC1HDAC2ALDH1A1CETP | |
| SCHEMBL12819959 | 0.81 | MEN1 (0.62) | HDAC3HDAC1HDAC2ALDH1A1CETP | |
| SCHEMBL13642228 | 0.81 | HDAC1 (0.60) | HDAC3HDAC1HDAC2ALDH1A1CETP | |
| SCHEMBL4223097 | 0.80 | HDAC1 (1.00) | HDAC3HDAC1HDAC2ALDH1A1CETP | |
| SCHEMBL27294525 | 0.79 | KMT2A (0.72) | ALDH1A1MEN1KMT2APLAUHPGD | |
| SCHEMBL3335404 | 0.77 | HDAC1 (0.84) | HDAC3HDAC1HDAC2ALDH1A1CETP | |
| SCHEMBL3118143 | 0.74 | ALDH1A1 (0.48) | HDAC3HDAC1HDAC2ALDH1A1MEN1 | |
| SCHEMBL28256535 | 0.73 | CETP (0.77) | HDAC3HDAC1HDAC2ALDH1A1CETP | |
| SCHEMBL28258088 | 0.73 | CETP (0.77) | HDAC3HDAC1HDAC2ALDH1A1CETP | |
| SCHEMBL12323604 | 0.73 | CETP (0.77) | HDAC3HDAC1HDAC2ALDH1A1CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203692-A1 | NOVEL CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203692-A1 | NOVEL CHEMICAL COMPOUNDS | HIPK3, HIPK1, HIPK4 | HDAC3 1012/4885HDAC1 1549/4885HDAC2 2038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.