Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | FADS1 | O60427 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3004808 | 0.93 | FAAH (0.49) | FAAH | |
| SCHEMBL4386918 | 0.92 | PTGS2 (0.53) | FAAHPTGS2MEN1KMT2AMAPT | |
| SCHEMBL3004659 | 0.92 | PTGS2 (0.53) | FAAHPTGS2MEN1KMT2AMAPT | |
| SCHEMBL3008722 | 0.92 | FAAH (0.51) | FAAHMEN1KMT2AMAPT | |
| SCHEMBL2170746 | 0.91 | FAAH (0.54) | FAAHMEN1KMT2AMAPT | |
| SCHEMBL3004494 | 0.90 | TP53 (0.46) | FAAHFADS1PTGS2TP53MEN1 | |
| SCHEMBL3005608 | 0.89 | FAAH (0.47) | FAAHFADS1PTGS2TP53MEN1 | |
| SCHEMBL4099153 | 0.88 | FAAH (0.51) | FAAHTP53MEN1KMT2AMAPT | |
| SCHEMBL4094533 | 0.88 | FAAH (0.53) | FAAHTP53MEN1KMT2AMAPT | |
| SCHEMBL3005187 | 0.88 | FAAH (0.49) | FAAHPTGS2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2610244-A1 | Indole compounds | Ironwood Pharmaceuticals, Inc. (US) | 2013-07-03 | — | — | EP | disclosed |
| US-20090118503-A1 | FAAH INHIBITORS | IRONWOOD PHARMACEUTICALS, INC. | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118503-A1 | FAAH INHIBITORS | FAAH, FAAH2, CNR2 | FAAH 1/4885FADS1 87/4885PTGS2 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.