SCHEMBL408906

SCHEMBL408906

CCOC(=O)c1ccccc1Br

nearest known ligand 0.74

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.74
ALDH1A1 P00352 4/20 0.62
HSD17B10 Q99714 3/20 0.62
CDC25B P30305 1/20 0.53
RAB9A P51151 3/20 0.53
NPC1 O15118 2/20 0.53
HPGD P15428 1/20 0.53
KDM4E B2RXH2 3/20 0.52
RXFP1 Q9HBX9 2/20 0.52
F2R P25116 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
KMT2A Q03164 2/20 0.51
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL15544606 0.98 TSHR (0.71) TSHRALDH1A1HSD17B10CDC25BRAB9A
SCHEMBL28628629 0.98 TSHR (0.71) TSHRALDH1A1HSD17B10CDC25BRAB9A
SCHEMBL5096210 0.86 TSHR (0.65) TSHRALDH1A1HSD17B10CDC25BKDM4E
Diethyl Phthalate SCHEMBL22296 0.86 TSHR (1.00) TSHRALDH1A1HSD17B10CDC25BNPC1
Diethyl Phthalate SCHEMBL29404255 0.86 TSHR (1.00) TSHRALDH1A1HSD17B10CDC25BNPC1
Diethyl Phthalate SCHEMBL5306972 0.86 TSHR (1.00) TSHRALDH1A1HSD17B10CDC25BNPC1
SCHEMBL265052 0.85 TSHR (0.63) TSHRALDH1A1HSD17B10CDC25BRAB9A
SCHEMBL28002169 0.85 ALDH1A1 (0.76) TSHRALDH1A1HSD17B10RAB9ANPC1
Ethyl Benzoate SCHEMBL6867262 0.84 SMN1; SMN2 (0.54) TSHRALDH1A1HSD17B10RAB9ANPC1
SCHEMBL8178343 0.84 TSHR (0.61) TSHRALDH1A1HSD17B10CDC25BHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 633 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116331361-A Integrated shock-resistant automobile sound-insulation front wall plate with built-in hidden water guide groove 江苏环宇汽车零部件有限公司 2023-06-27 CN claimed
CN-109837082-B Electroluminescent material and preparation method and application thereof 东莞伏安光电科技有限公司 2022-07-26 CN claimed
CN-108484541-B Synthesis method of 5-formyl furan-2-ethyl nitrobenzoate 济南大学 2022-06-07 CN claimed
CN-114560834-A Spirodiclofen hapten, antigen and antibody as well as preparation method and application thereof 西南大学 2022-05-31 CN claimed
CN-112354551-B Monoatomic metal photocatalyst, preparation method thereof and application thereof in carbon-oxygen cross-coupling reaction 中国科学院化学研究所 2021-12-31 CN claimed
CN-111763455-A Preparation method of heat-insulating high-shading paint 江苏大亚新型包装材料有限公司 2020-10-13 CN claimed
CN-110698377-A Fluorescent small molecular probe based on single benzene ring and synthetic method thereof 西安工程大学 2020-01-17 CN claimed
CN-109837082-A A kind of electroluminescent material and the preparation method and application thereof 华南协同创新研究院 2019-06-04 CN claimed
CN-104592222-B The preparation method of antiplatelet drug AZD6482 苏州明锐医药科技有限公司 2016-08-24 CN claimed
CN-104592222-A Preparation method for antiplatelet medicine AZD6482 SUZHOU MIRACPHARMA TECHNOLOGY CO LTD 2015-05-06 CN claimed
US-12607789-B2 Display panel and method of manufacturing the same and electronic device SAMSUNG ELECTRONICS CO., LTD. (KR) 2026-04-21 US disclosed
EP-4658641-A1 NOVEL COMPOUNDS THAT CAN BE USED AS THERAPEUTIC AGENTS Xeniom GmbH (DE) 2025-12-10 EP disclosed
US-20250263399-A1 CBL-B MODULATORS AND USES THEREOF SCHRÖDINGER, INC. 2025-08-21 US disclosed
US-12325697-B2 CBL-B modulators and uses thereof NIMBUS CLIO, INC. (US) 2025-06-10 US disclosed
EP-4540238-A1 MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME Monte Rosa Therapeutics AG (CH) 2025-04-23 EP disclosed
US-4162241-A NEUTRALIZED SULFONATED BUTYL RUBBER OR DIENE-ETHYLENE-PROPYLENE TERPOLYMER EXXON RESEARCH & ENGINEERING CO. (US) 1979-07-24 US disclosed
EP-0002354-A1 A process for sulphonating elastomeric polymers EXXON RESEARCH AND ENGINEERING COMPANY (US) 1979-06-13 EP disclosed
US-4105647-A SOLUTION POLYMERIZATION USING A FRIEDEL-CRAFTS OF ZIEGLER-TYPE CATALYST EXXON RESEARCH & ENGINEERING CO. (US) 1978-08-08 US disclosed
US-4088677-A CORROSION INHIBITORS, COMPLEXING AGENTS, FLAME RETARDANTS, PHARMACEUTICAL INTERMEDIATES HOECHST AKTIENGESELLSCHAFT (DT) 1978-05-09 US disclosed
US-3974243-A Carboxyphenyl-alkylphosphinic esters HOECHST AKTIENGESELLSCHAFT (DT) 1976-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12607789-B2 Display panel and method of manufacturing the same and electronic device CD63, CD2, NECTIN4 TSHR 3710/4885ALDH1A1 549/4885HSD17B10 4369/4885
US-20250263399-A1 CBL-B MODULATORS AND USES THEREOF CBLB, CBL, CBLC TSHR 3636/4885ALDH1A1 4641/4885HSD17B10 3698/4885
US-12325697-B2 CBL-B modulators and uses thereof CBLB, CBL, CBLC TSHR 3636/4885ALDH1A1 4641/4885HSD17B10 3698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.